Author(s): Nandini R. Pai, Swapnali Suhas Patil

Email(s): Email ID Not Available

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Address: Nandini R. Pai and Swapnali Suhas Patil*
Department of Chemistry, D. G. Ruparel College, Mahim, Mumbai, Maharashtra, India
*Corresponding Author

Published In:   Volume - 6,      Issue - 9,     Year - 2013


ABSTRACT:
A simple, rapid and sensitive RP-HPLC method developed for quantitative determination of an angina pectoris drug i.e. 2,3,4-Trimetazidine Dihydrochloride and its three related substances using C18 150 X 4.6, 5um column and mobile phase consisting of aqueous buffer and Methanol. This method was validated as per ICH guideline for parameters including specificity, precision, linearity, accuracy, limit of detection and limit of quantization. The method was found to be stability –indicating and useful for analysis of drug’s related substances.


Cite this article:
Nandini R. Pai, Swapnali Suhas Patil. A Novel RP-HPLC Method for Quantitative Determination of an Angina Pectoris Drug and Related Substance. Research J. Pharm. and Tech. 6(9): September 2013; Page 1014-1018.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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