Author(s): Girish Pai K., Baldha Parinkumar Dhirajlal

Email(s): girish.pai@manipal.edu

DOI: Not Available

Address: Girish Pai K.1* and Baldha Parinkumar Dhirajlal2
1Assistant Professor (Senior Grade), Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka-576104
2Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka State, India-576104
*Corresponding Author

Published In:   Volume - 6,      Issue - 8,     Year - 2013


ABSTRACT:
Compressed multiple unit pellet tablets/multiple unit particulate or pellet systemsare commonly called as Multiple Unit Particulate Systems (MUPS). MUPSare composed of polymer coated subunits namely pellets; which are embedded in an inert excipients matrix designed to overcome the difficulties in administering capsules and for improved physico-chemical stability compared to suspensions. The functional coating like drug coating, barrier coating, enteric polymer coating is usually applied in a fluid bed coating processor that provides each subunit with the characteristic desired drug release properties. The size, shape and surface morphology of the pellets to be coated are the criterions for coating of pellets. Design of MUPS involves formulating pellets by different techniques and further compression of these pellets into rapidly disintegrating tablets; disintegrate rapidly in the oral cavity for the delivery of coated pellets into the gastrointestinal tract or at the site of release of the drug. That’s why MUPS is a new trend in formulation industry to deliver the drug of categories like Antacid, Non-steroidal anti-inflammatory drugs (NSAIDs), Colon specific drugs etc. In spite of the challenges like content uniformity of the compressed tablets, ability of the film to withstand compression force; MUPS occupy a prominent role in formulating drugs due to their improved patient compliance, process feasibility and therapeutic advantages.


Cite this article:
Girish Pai K., Baldha Parinkumar Dhirajlal. Multiple Unit Particle System (MUPS):Novel technology for preparation of Extended Release (ER) tablets. Research J. Pharm. and Tech. 6(8): August 2013; Page 856-864.


Recomonded Articles:

Author(s): Jino Elsa Thomas, Usha Y Nayak*, Jagadish PC, Koteshwara KB

DOI: 10.5958/0974-360X.2017.00007.5         Access: Open Access Read More

Author(s): Abhirup Dey, Mangala Lakshmi Ragavan, Sanjeeb Kumar Mandal, Nilanjana Das

DOI: 10.5958/0974-360X.2017.00136.6         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): Deepak Karki, Gururaj S. Kulkarni, Shivakumar Swamy, Sheeba FR

DOI: 10.5958/0974-360X.2017.00750.8         Access: Open Access Read More

Author(s): B. Thawkar, M. Kale, M. Oswal, K. Maniyar, K. Kadam, S. Kamat

DOI: 10.5958/0974-360X.2016.00044.5         Access: Open Access Read More

Author(s): Priya P. Munshi, D.S. Mohale, R. Akkalwar, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Sandesh More, Javed Mirza, Nanasaheb Kale, Mayur Gandhi, Rakesh Chaudhari

DOI: Not Available         Access: Open Access Read More

Author(s): Mahadeva Rao US, San San Oo, Nurul Liana Sabrin, Norsyahira Syazwana Mohd Razali, Khairunnisa Khalid, Nurul Farihah Mohamed Nadzari, Thant Zin

DOI: 10.5958/0974-360X.2017.00065.8         Access: Open Access Read More

Author(s): Mahanthesh M.C., Girendra Gautam, Jalalpure S.S.

DOI: 10.5958/0974-360X.2017.00250.5         Access: Open Access Read More

Author(s): Yarnykh T.G., Azarenko Iu. M., Buryak M.V., Bubilieva L. A.

DOI: 10.5958/0974-360X.2016.00115.3         Access: Open Access Read More

Author(s): Barokar A.A., Wagh R.D., Baviskar D.T., Shaikh T.J.

DOI: Not Available         Access: Open Access Read More

Author(s): Amutha K*, Ashok Kumar A, Godavari A

DOI: 10.5958/0974-360X.2017.00100.7         Access: Open Access Read More

Author(s): Krishnendu Acharya*, Somanjana Khatua, Salman Sahid

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags