Ashif, Jyoti Sharma, Gopal Ji Baranwal, Shamim Ahmad, M Shamsher Alam
Ashif1, Jyoti Sharma1, Gopal Ji Baranwal1, Shamim Ahmad2, M Shamsher Alam1*
1Department of Pharmaceutical Chemistry, Translam Institute of Pharmaceutical Education and Research, Mawana Road, Meerut 250001, U.P. India
2Department of Pharmacognosy, Translam Institute of Pharmaceutical Education and Research, Mawana Road, Meerut 250001, U.P. India
Volume - 6,
Issue - 7,
Year - 2013
Among the bicyclic non-aromatic nitrogen heterocycles, phthalimides are an interesting class of compounds with a large range of applications. Phthalimides have served as starting materials and intermediates for the synthesis of many types of alkaloids and pharmacophores. Recently, phthalimide and some of its derivatives have proved to have important biological effects similar or even higher than known pharmacological molecules and so their biological activity is being a subject of biomedical research. Phthalimides have received attention due to their antibacterial, antifungal, analgesic, antitumour, anxiolytic and anti HIV-1 activities. When phthalimide is subjected to Mannich condensation, it may yield Mannich bases which may display more potent biological activities. The present review focuses the novel synthesized phthalimides having important biological activities.
Cite this article:
Ashif, Jyoti Sharma, Gopal Ji Baranwal, Shamim Ahmad, M Shamsher Alam. Phthalimides: Biological Profile and Recent Advancements. Research J. Pharm. and Tech 6(7): July 2013; Page 711-714.