Author(s): A. K. Patel, Raj K. Prasad, S. S. Gautam, Omprakash

Email(s): rajdavv2007@gmail.com

DOI: Not Available

Address: A. K. Patel1*, Raj K. Prasad1, S. S. Gautam1, Omprakash2
1Shambhunath Institute of Pharmacy, Jhalwa, Near IIIT, Allahabad, U.P., India-211012
2R. K. G. Institute of Pharmacy, Gaziabad, U. P., India
*Corresponding Author

Published In:   Volume - 6,      Issue - 6,     Year - 2013


ABSTRACT:
The purpose of this study was to develop formulations and systematically evaluate in vitro performances of super porous hydrogel composites of Metoprolol Tartrate. A cross-over design was employed in formulating the SPHC with variation in polymer concentration (N, N-methylene-bisacrylamide (1-3%) and Ac-Di-Sol (200-300mg)). Study the effect of variation on swelling time, mechanical properties and in vitro drug release. The result shows that increase in Ac-Di-Sol concentration also increase in mechanical strength where as 2% of Bis concentration have less swelling time. In-vitro release data show that best result at optimum concentration of Bis (2%) and Ac-Di-Sol concentration (250mg).


Cite this article:
A. K. Patel, Raj K. Prasad, S. S. Gautam, Omprakash. Formulation and Evaluation of Super Porous Hydrogel Composites of Metoprolol Tartrate. Research J. Pharm. and Tech 6(6): June 2013; Page655-658.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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