Author(s): Shinde Sunita S., Amol S. Shete, Patil Manisha V., J.I. Disouza

Email(s): sunithashinde@gmail.com

DOI: Not Available

Address: Shinde Sunita S.1*, Amol S. Shete2 Patil Manisha V.1, J.I. Disouza1
1Department of Pharmaceutics, Tatayasaheb Kore College of Pharmacy, Warananagar
2Department of Pharmacognosy, Ashokrao Mane College of Pharmacy, Pethvadgaon, Ambap
*Corresponding Author

Published In:   Volume - 6,      Issue - 6,     Year - 2013


ABSTRACT:
The purpose of this research work to prepare a sustained release tablet of Theophylline. by direct compression method. Different hydrophilic polymers like hydroxypropyl methyl cellulose and xanthan gum were used. The effects of polymers concentration on drug release profile were investigated. Cumulative % release of drug for 1st hour and 8th hour were studied In formulation Theophylline Sustained Release tablet, direct compression employed for preparation of tablets possessing optimized characteristics (batches B3to B5). The amount of HPMC and Xanthan gum were calculated and selected for optimize batch. Results of the present study confirmed that the hydrophilic polymers and hardness plays a major role in drug release. As the hydrophilic polymers and hardness of the tablets increased the drug release was prolonged.


Cite this article:
Shinde Sunita S., Amol S. Shete, Patil Manisha V., J.I. Disouza. Formulation and Evaluation of Sustained Release Tablets using Direct Compression Method. Research J. Pharm. and Tech 6(6): June 2013; Page 637-640.


Recomonded Articles:

Author(s): Ahmed Hilal Sheriff, Preetham Prasad Nittla

DOI: 10.5958/0974-360X.2019.00968.5         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Deepak Karki, Gururaj S. Kulkarni, Shivakumar Swamy, Sheeba FR

DOI: 10.5958/0974-360X.2017.00750.8         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Rekha Kallam, Padma Sree K, Srinivas Arutla, MA Bari

DOI: Not Available         Access: Open Access Read More

Author(s): Amutha K*, Ashok Kumar A, Godavari A

DOI: 10.5958/0974-360X.2017.00100.7         Access: Open Access Read More

Author(s): Y. Prem Kumar, K. Vinod Kumar, V. Sai Kishore

DOI: Not Available         Access: Open Access Read More

Author(s): Yarnykh T.G., Azarenko Iu. M., Buryak M.V., Bubilieva L. A.

DOI: 10.5958/0974-360X.2016.00115.3         Access: Open Access Read More

Author(s): Mahanthesh M.C., Girendra Gautam, Jalalpure S.S.

DOI: 10.5958/0974-360X.2017.00250.5         Access: Open Access Read More

Author(s): Mahadeva Rao US, San San Oo, Nurul Liana Sabrin, Norsyahira Syazwana Mohd Razali, Khairunnisa Khalid, Nurul Farihah Mohamed Nadzari, Thant Zin

DOI: 10.5958/0974-360X.2017.00065.8         Access: Open Access Read More

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Author(s): Jayesh M Jain, Dinesh M Sakarkar, Shajahan Abdul, Mangesh E Bhad, Anil V Chandewar and Sunil B Jaiswal

DOI: Not Available         Access: Closed Access Read More

Author(s): Nur Qistina Binti Ahmad Fauzi, Vishnupriya V, Gayathri R.

DOI: 10.5958/0974-360X.2016.00240.7         Access: Open Access Read More

Author(s): Oruganti Sai Koushik, V. Himaja, P. Srinivasa Babu, Ramadoss Karthikeyan

DOI: 10.5958/0974-360X.2015.00298.X         Access: Open Access Read More

Author(s): Jagdale Swati C., Hable Asawaree A., Kuchekar Bhanudas S., Chabukswar Aniruddha R.

DOI: Not Available         Access: Open Access Read More

Author(s): Manisha N. Trivedi, Archana Khemani, Urmila D. Vachhani, Charmi P. Shah, D.D. Santani

DOI: Not Available         Access: Open Access Read More

Author(s): Saleem M.A., Sudhir S. Pange, Shaikh Ahnaf Umair, Vishal Kumar Singh

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags