Author(s): Bhagyashree Purohit, Naveen Gupta, Shailesh Jain

Email(s): bhagyashree.purohit@yahoo.com

DOI: Not Available

Address: Bhagyashree Purohit*, Naveen Gupta, Shailesh Jain
Faculty of Pharmacy, VNS Group of Institutions, Bhopal (M.P.)
*Corresponding Author

Published In:   Volume - 6,      Issue - 4,     Year - 2013


ABSTRACT:
The objective of present study was to develop diclofenac sodium organogel using sorbitan monoesters. Various organogels were prepared using isopropyl myristate, tween 80, sorbitan monostearate and sorbitan monopalmitate as organogelator. The formulated organogels were evaluated for their appearance, homogeneity, pH, viscosity, spreadibility, and % drug content and drug release. The drug release study was carried out using Franz diffusion cell.Rat skin of suitable size was clamped on to the cell. Organogel containing 7.5% of sorbitan monostearate showed highest drug release rate, however on further increasing the organogelator concentration the drug release rate was found to decrease. This decrease in drug release rate can be attributed to entrapment of drug into fiber network which hinder drug release. Organogel containing sorbitan monopalmiatate showed a lower drug release rate


Cite this article:
Bhagyashree Purohit, Naveen Gupta, Shailesh Jain. Formulation and Evaluation of Diclofenac sodium Organogel. Research J. Pharm. and Tech. 6(4): April 2013; Page 375-378.


Recomonded Articles:

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): Kumkum Sarangdevot, Bhawani Singh Sonigara, Amul Mishra, K. C. Gupta, Surbhi Sharma

DOI: Not Available         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Y. Prem Kumar, K. Vinod Kumar, V. Sai Kishore

DOI: Not Available         Access: Open Access Read More

Author(s): Rao Rekha, Goswami Anju, Shekhar Shishant, Mahant Sheefali, Nanda Sanju

DOI: Not Available         Access: Open Access Read More

Author(s): Bhagyashree Purohit, Naveen Gupta, Shailesh Jain

DOI: Not Available         Access: Open Access Read More

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

Author(s): Subhashis Debnath1*, Gampa Vijay Kumar2, Satayanarayana S.V.3

DOI: Not Available         Access: Open Access Read More

Author(s): Surbhi Sharma1*, M.S. Ashawat2 and N.S. Solanki3

DOI: Not Available         Access: Open Access Read More

Author(s): SK Jain, R Chandra, AK Rai

DOI:         Access: Open Access Read More

Author(s): Suchithra. A. B, S. Jeganath, E. Jeevitha

DOI: 10.5958/0974-360X.2019.01073.4         Access: Open Access Read More

Author(s): Bayu Eko Prasetyo, Karsono, Sakro Mega Maruhawa, Lia Laila

DOI: 10.5958/0974-360X.2018.00707.2         Access: Open Access Read More

Author(s): Mohd Yasir, Iti Chauhan, Misbahu J. Haji, Abdurazak J. Tura1, Prasoon K. Saxena

DOI: 10.5958/0974-360X.2018.00523.1         Access: Open Access Read More

Author(s): Vaisakh M. N., Anima Pandey

DOI: Not Available         Access: Open Access Read More

Author(s): Srikanth, Anand Kumar Y, Mallikarjuna Setty C

DOI: 10.5958/0974-360X.2019.00466.9         Access: Open Access Read More

Author(s): Narayana Charyulu R, Arjun Muaralidharan, Sandeep DS

DOI: 10.5958/0974-360X.2018.00028.8         Access: Open Access Read More

Author(s): Shirsath SC, Patil PB, Mutha SS, Bhosale AV, Hardikar SR

DOI:         Access: Open Access Read More

Author(s): Mrityunjoy Majumdar, Arnab Samanta, Amitava Roy

DOI: 10.5958/0974-360X.2016.00427.3         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags