Yogesh M. Bagad, Mayur R. Bhurat, Anil U. Tatiya, Sanjay J. Surana, Shashikant D. Barhate
Yogesh M. Bagad2*, Mayur R. Bhurat2, Anil U. Tatiya1, Sanjay J. Surana1,
Shashikant D. Barhate2
1Department of Pharmacognosy, R.C. Patel College of Pharmacy, Shirpur (MS) – 425405
2Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, Jalgaon (MS)-424206.
Volume - 6,
Issue - 4,
Year - 2013
In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. The wound healing parameters were evaluated by using incision, and dead space wounds in extract-treated rats and controls. free radical are generated in side every human body these free radicals are beneficial if they are generated in small amount but if they are generated in huge amount they are harmful to our body. At low concentration free radicals can stimulate the proliferation of cells as well as the formation of connective tissue and new blood vessels. "Skin wounds are rich in free radicals. There was a longer-lasting free radical effect in the wounds that had been treated with acetone and aqueous extract of LBR. The wound healing activity of acetone and aqueous extracts of Bridelia airyshawii Spreng. (Euphorbiaceae) was evaluated on incision and dead space wound models on albino rats. The healing activity was more significant in acetone extract treated animals. In incision wound models the wound healing process was evidenced by increase in the tensile strength. While in dead space wound model, the weight of the granuloma and tensile strength were increased indicating the increase in collagenation. The results were also compared with control and standard drug.
Cite this article:
Yogesh M. Bagad, Mayur R. Bhurat, Anil U. Tatiya, Sanjay J. Surana, Shashikant D. Barhate. Evaluation of antioxidant and wound healing activity of the leaves of Bridelia airyshawii spreng. Research J. Pharm. and Tech. 6(4): April 2013; Page 351-355.