In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica

V.A. Kangralkar; A.R. Kulkarni

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica

Author(s): V.A. Kangralkar, A.R. Kulkarni

Email(s): vishnuak@rediffmail.com

DOI: Not Available

Address: V.A. Kangralkar1* and A.R. Kulkarni2
1Maratha Mandal’s College of Pharmacy, Belgaum Karnataka, 1Research Scholar, Karpagam University Coimbatore.
2Department of Pharmacology, SET’s College of Pharmacy, Dharwad- 580 002, India.
*Corresponding Author

Published In: Volume - 6, Issue - 11, Year - 2013

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ABSTRACT:
Aristolochia indica root extract (alcoholic) was screened for its antitumor activity on proliferation of HT29 colon cancer cell line. The activity was determined by microculture tetrazolium viability (MTT) assay. The different concentrations (100, 50, 25, 12.5, 6.25and 3.125 µgram/ml) were taken and cells were exposed with the extract. The % cytotoxicity produced in MTT assay at100 Microgram/ml was 69.21 with IC50 of 28.56 . From these results it was observed that alcoholic extract of Aristolochia indica root has significant cytotoxic activity.

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Cite this article:
V.A. Kangralkar, A.R. Kulkarni. In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica. Research J. Pharm. and Tech. 6(11): November 2013; Page 1240-1241.

Cite(Electronic):
V.A. Kangralkar, A.R. Kulkarni. In Vitro Cytotoxic Activity of Alcoholic Extract of Aristolochia indica. Research J. Pharm. and Tech. 6(11): November 2013; Page 1240-1241. Available on: https://rjptonline.org/AbstractView.aspx?PID=2013-6-11-5