Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Malabsorption of Drugs in Gastrointestinal Diseases: a Review

Author(s): Lakshmi Prasanna J., Deepthi B., Rama Rao N

Email(s): prasanna_994@yahoo.co.in

DOI: Not Available

Address: Lakshmi Prasanna J.*, Deepthi B.*, Rama Rao N.
Department of pharmaceutics, Chalapathi Institute of Pharmaceutical Sciences, Lam, Guntur- 522034
*Corresponding Author

Published In:   Volume - 6,      Issue - 1,     Year - 2013

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ABSTRACT:
Most long term treatments follow the oral administration due to its ease and convenience of administration. After oral administration of any drug, the plasma concentration time curve is a function of many simultaneously operating kinetic processes. The steady state plasma concentration is achieved when the amount of drug absorbed equals the amount of drug eliminated. Both amount and rate of drug absorbed may be altered by diseases which in turn alter other kinetic processes. The amount of drug absorbed is simultaneously affected by physicochemical factors of drug and physiological factors that operate in gut which are also altered by the disease state. The present review focuses on the way in which the absorption of drugs is altered in various conditions of gastro intestinal tract.


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Cite this article:
Lakshmi Prasanna J., Deepthi B., Rama Rao N. Malabsorption of Drugs in Gastrointestinal Diseases: a Review. Research J. Pharm. and Tech. 6(1): Jan. 2013; Page 29-33.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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