2-(1H-1,2,3-benzotriazol-1-yl)-N-phenylacetamide derivatives find useful as anti-infective agents and substitution of bentriazole produces more potent anti-infective agents. Derivatives of benzotriazole substituted 2-(1H-1,2,3-benzotriazol-1-yl)-N-phenylacetamide are synthesized and anti microbial activities have been measured against Norfloxacine and Ketoconazole as standards drugs. It is found that the derivatives from 1a to Va are shown to produce good anti microbial actions against, S. Aureus, S. Pygens, B. Subtilis, E.coli, P. Aerigenosa, C Albicanse, A Niger. The all the derivatives show satisfactory anti-microbial activities.
Cite this article:
C. M. Jamkhandi, John Intru Disouza. Synthesis and Antimicrobial Evaluation of 2-(1H-1,2,3-Benzotriazol-1-yl)-N-Phenylacetamide Derivatives. Research J. Pharm. and Tech. 5(8): August 2012; Page 1072-1075.