S. P. Wate, G. B. Bhagwat, A. S. Mundhey, P. M. Bawankar
S. P. Wate, G. B. Bhagwat*, A. S. Mundhey and P. M. Bawankar
Sharad Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur-441 110 (M.S.)
Volume - 5,
Issue - 8,
Year - 2012
A simple, accurate, economical and reproducible procedure for simultaneous estimation of Prochlorperazine Maleate (PCM) and Pyridoxine Hydrochloride (PDH) in their tablet dosage form is described. The method involves absorbance of measurement at 267.5 nm (isobestic point) and 290.5 nm (?max of Pyridoxine Hydrochloride), in 0.3 N HCl. Both drugs obey Beer-Lambert’s law in concentration range of 1-5 µg/ml (PCM) and 5-25 µg/ml (PDH). The results of analysis have been validated statistically and by recovery studies.
Cite this article:
S. P. Wate, G. B. Bhagwat, A. S. Mundhey, P. M. Bawankar. Absorption Ratio Method for Simultaneous Estimation of Prochlorperazine Maleate and Pyridoxine Hydrochloride in Tablet. Research J. Pharm. and Tech. 5(8): August 2012; Page 1112-1113.