Author(s): Urvi S. Shah, K.N. Patel

Email(s): urvisshah@gmail.com

DOI: Not Available

Address: Urvi S. Shah1*, K.N. Patel2
1Singhania University, Jhunjhunu, Rajasthan, India.
2SAL Institute of Pharmacy, Ahmadabad, Gujarat, India.
*Corresponding Author

Published In:   Volume - 5,      Issue - 7,     Year - 2012


ABSTRACT:
We investigated the antihyperlipidemic activity of Strychnos potatorum seeds. The current study was undertaken to assess the hypolipidemic, hypocholesterolemic and hypotriglyceridemic potential of the seeds using triton WR-1339 (Tyloxapol) induced hyperlipidemia in rats. The animals were divided into five groups: control, hyperlipidemic, hyperlipidemic plus Atorvastatin, hyperlipidemic plus Strychnos potatorum seed powder 100mg/kg and Strychnos potatorum seed powder 200mg/kg. Hyperlipidemia was induced by single intraperitoneal injection of triton WR 1339 at a dose of 400mg/kg. Intragastric administration of seed powder significantly (p<0.05) decreased serum total cholesterol, triglycerides, low density lipoprotein cholesterol, very low density lipoprotein cholesterol levels in rats in dose dependent and time dependent manner compared to hyperlipidemic group. Thus, the findings of the investigation suggest that Strychnos potatorum seeds exhibited quite competitive potential when compared with reference drug Atorvastatin against experimentally induced hyperlipidemia.


Cite this article:
Urvi S. Shah, K.N. Patel. Effects of Strychnos potatorum Linn. seeds on Triton WR 1339 Induced Hyperlipidemia in Rats. Research J. Pharm. and Tech. 5(7): July 2012; Page 901-904.


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): S. Subasree, Karthikeyan Murthykumar, Dhanraj

DOI: 10.5958/0974-360X.2016.00116.5         Access: Open Access Read More

Author(s): Raj Kumar R, Praveen D, Palani Shanmugasundaram

DOI: 10.5958/0974-360X.2016.00164.5         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Anis Fathima. A. G, Vara Prasanna Rao, P. Shanmugasundaram

DOI: 10.5958/0974-360X.2017.00385.7         Access: Open Access Read More

Author(s): Barokar A.A., Wagh R.D., Baviskar D.T., Shaikh T.J.

DOI: Not Available         Access: Open Access Read More

Author(s): V Rajesh Babu, Syeda Rana Nikhat, P Nivethithai, SH Areefulla

DOI: Not Available         Access: Open Access Read More

Author(s): R. Suresh, D. Benitojohnson, C. Maheswari, R. Venkatnarayanan, R.Manavalan

DOI: 10.5958/0974-360X.2017.00128.7         Access: Open Access Read More

Author(s): Rao Rekha, Goswami Anju, Shekhar Shishant, Mahant Sheefali, Nanda Sanju

DOI: Not Available         Access: Open Access Read More

Author(s): Karthikeyan D, Vijayakumar S, Pandey V.P, Nandha Kumar J, Sengottuvelu S, T. Sivakumar T.

DOI:         Access: Open Access Read More

Author(s): Tapan Kumar Giri, Saumya Mishra, Dulal Krishna Tripathi

DOI: Not Available         Access: Open Access Read More

Author(s): Hitesh Jain, Rushi Panchal, Dilrose Pabla, Jaimini Patel, Mansi Khirwadkar

DOI: Not Available         Access: Open Access Read More

Author(s): H.B. Pagar, U.P. Shinde, Y.S. Agrawal, S.D. Barhate, T.S. Luhade, R.O. Sonawane

DOI: Not Available         Access: Open Access Read More

Author(s): Sandra Sajen, Jephin Varughese Jose, Sandeep Bukke, Chaithanya Sudha M, Saladi S.V. Subbarao, V.R. Mandla

DOI: 10.5958/0974-360X.2017.00286.4         Access: Open Access Read More

Author(s): Trophimus Gnanabagyan Jayakaran, Vignesh R, Shankar P

DOI: 10.5958/0974-360X.2019.00700.5         Access: Open Access Read More

Author(s): Jagdale Swati C., Hable Asawaree A., Kuchekar Bhanudas S., Chabukswar Aniruddha R.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags