Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)


Submit Article

In vitro study of Cayratia trifolia (L.) Domin on isolated rat hemi-diaphragm by glucose uptake method

Author(s): Shikha Batra, Nikhil Batra, Anil Pareek, Badri Prakash Nagori

Email(s): shikhabatrapc@yahoo.co.in

DOI: Not Available

Address: Shikha Batra*, Nikhil Batra, Anil Pareek, Badri Prakash Nagori
Lachoo Memorial College of Science & Technology, Pharmacy Wing, Jodhpur-342 003, Rajasthan (India)
*Corresponding Author

Published In:   Volume - 5,      Issue - 5,     Year - 2012

 View HTML        View PDF

ABSTRACT:
In the present investigation, Cayratia trifolia (L.) Domin, folklore antidiabetic plant, has been evaluated for its hypoglycaemic activity. This activity was studied using the glucose uptake by isolated rat hemi-diaphragm in vitro model. The powdered root of this plant was successively extracted with petroleum ether, chloroform, ethyl acetate and ethanol. Preliminary phytochemical investigations showed the presence of flavanoids in the ethanolic extract. This extract increased the uptake of glucose by isolated rat hemi-diaphragm significantly (P<0.05). It appears that the extract has direct peripheral action on glucose uptake. Results strongly suggested that C. trifolia has the potential for the treatment of diabetes mellitus caused in the consequences of resistance to stimulatory effect of insulin on GLUT-4 protein.


Keywords:

Cite this article:
Shikha Batra, Nikhil Batra, Anil Pareek, Badri Prakash Nagori. In vitro study of Cayratia trifolia (L.) Domin on isolated rat hemi-diaphragm by glucose uptake method. Research J. Pharm. and Tech. 5(5): May2012; Page 691-693.


Recomonded Articles:

Comparative Evaluation of Quality Control Parameters of Marketed Antidiabetic Tablet

Author(s): S.M. Charjan, S.K. Bais, R.R. Shiradkar, R.L. Bakal, V.M. Durge, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Free Radical Scavenging Activity and Total Antioxidant Capacity of Tin Chlorophyllin from Morinda citrifolia L.

Author(s): Pavithra. S, N. Banu

DOI: 10.5958/0974-360X.2017.00091.9         Access: Open Access Read More

Antidiabetics Review on Natural Products

Author(s): Surendra Nath Pandeya, Rajeev Kumar, Arun Kumar, Ashish Kumar Pathak

DOI: Not Available         Access: Open Access Read More

Phytochemistry, Traditional uses and Pharmacology of Rhododendron arboreum: A Review

Author(s): Som K. Madhvi, Manik Sharma, Javaid Iqbal, Mohd Younis

DOI: 10.5958/0974-360X.2019.00785.6         Access: Open Access Read More

In vitro study of Cayratia trifolia (L.) Domin on isolated rat hemi-diaphragm by glucose uptake method

Author(s): Shikha Batra, Nikhil Batra, Anil Pareek, Badri Prakash Nagori

DOI: Not Available         Access: Open Access Read More

Hypoglycemic Activity of Curculigo orchioides Gaertn in Normal and Streptozotocin Induced Diabetic Rats

Author(s): AK Jain, Naveen Sharma, Amit Upadhyay, Ashish Dixit

DOI: Not Available         Access: Open Access Read More

Study of Antidiabetic Activity of Cow Urine and Its Concentrate

Author(s): S. P. Wate, N. J. Duragkar, M. R. Tajne, S. S. Jadhav

DOI: Not Available         Access: Open Access Read More

An Overview on Hepatoprotective Activity of Natural Products

Author(s): Subin Mary Zachariah, N. Aleykutty, Vidya Viswanad, Halima O.A.

DOI: Not Available         Access: Open Access Read More

Vernonia amygdalina Del: A Mini Review

Author(s): Suleiman Danladi, Mohammed Alkassim Hassan, Idris Aliyu Masa’ud, Umar Idris Ibrahim

DOI: 10.5958/0974-360X.2018.00768.0         Access: Open Access Read More

Newer Biologically Active Pyridines: A Potential Review

Author(s): Nadeem Siddiqui, Waquar Ahsan, M. Shamsher Alam, Andalip, Bishmillah Azad, M. Jawaid Akhtar

DOI: Not Available         Access: Open Access Read More

A Study on Efficacy and Safety of Etanercept in Patients with Rheumatoid Arthritis

Author(s): A. Chaitanya, M. Ashok Kumar, A. Gokul Krishna, P. Shanmugasundaram.

DOI: 10.5958/0974-360X.2016.00396.6         Access: Open Access Read More

Anti-Hyperglycemic activity of the Leaves of Terminalia tomentosa against Normal and Alloxan Induced Diabetic Rats

Author(s): Sravanthi.Alladi, Sarath Prakash D., Ramesh Malothu, Nalini M., Srikanth Rao K.

DOI: Not Available         Access: Open Access Read More

An Overview of Treatment Challenges and the role of Herbal Antioxidants in Diabetes Mellitus

Author(s): Krishna Ravi, Rosmi Jose, Sumitha SK, Teena Johny, Krishnaveni K, Shanmuga Sundaram R, Sambath Kumar R

DOI: 10.5958/0974-360X.2017.00490.5         Access: Open Access Read More

Investigations on pharmacological constituent and antimicrobial efficacy of plant diffusate against clinical pathogens

Author(s): A. Rajeswari, S. Ramesh

DOI: Not Available         Access: Open Access Read More

Polymorphism: Quality rationalization, mitigation and authentication strategies with respect to regulatory compliances in pharmaceutical industry

Author(s): R.C. Pantola, Rakesh Bahuguna

DOI: Not Available         Access: Open Access Read More

Green Tea (Cardiac Tea) vs Java Tea (Kidney Tea): A Review

Author(s): Mrs. C. Maheswari*, Dr. R.Venkatnarayanan, Mr. P. Babu, Mr. C.S. Kandasamy

DOI: Not Available         Access: Closed Access Read More

Antidiabetic Effect of an Aqueous Extract of Pomegranate (Punica granatum L.) Peels in Normal and Alloxan Diabetic Rats

Author(s): Punasiya R, Joshi A, Patidar K

DOI: Not Available         Access: Open Access Read More

Literature Review on "Peek" Dental Implants

Author(s): Harsha. L, Anand S

DOI: 10.5958/0974-360X.2016.00364.4         Access: Open Access Read More

Drug Utilization and Evaluation of Gestational Diabetes Mellitus

Author(s): Maheshwari. P, Guna. B, Ranjith Kumar M, Renugadevi. S

DOI: 10.5958/0974-360X.2017.00768.5         Access: Open Access Read More

Possible Mosquito Control by Silver Nanoparticles Synthesized by Entomopathogenic Fungus Beauveria bassiana

Author(s): Marwah Amer Qamandar, Maan Abdul Azeez Shafeeq

DOI: 10.5958/0974-360X.2018.00198.1         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Quick Links

Latest Issues

Popular Articles


Recent Articles



Synthesis of Novel molecular hybrid 3-(4,5-dihydro-1H-pyrazol-3-yl)-4-hydroxy-2H-chromen-2-one derivatives and In Vitro α-glucosidase and α-amylase inhibitory activity
Hepatoprotective activity of Etlingera elatior (Jack) R.M. Smith Extract against CCl4 -induced Hepatic Toxicity in Male Wistar Rats
Anti-inflammatory activity of Ginger oleoresin mediated Silver nanoparticles
Formulation of Rhizobial Fertilizer for Leguminous Plant Vigna mungo Growth
Quantification Molecular Weight of Human Beta Defensin-2 and Human Beta Defensin-3 from Saliva of Caries patient
Preliminary Phytopharmacological Analysis, Proximate Composition Analysis and Product Development with the Leaves and Fruits of Muntingia calabura L.
UV-Spectroscopic Method development and Validation for simultaneous estimation of Doxylamine succinate and Pyridoxine hydrochloride in bulk and Pharmaceutical dosage form
Impact of Salbutamol in Chronic Obstructive Pulmonary Diseases patients: A prospective observational study on Clinical interventions
Spectrophotometric determination of Sulfasalazine drug in pure and Pharmaceutical preparation using sodium 1, 2-naphthoquinone-4-sulfonate (NQS) reagent
Synthesis and Molecular docking studies of some new Pyrazoline derivatives for Antimicrobial properties
Evaluation of Hepatoprotective activity in methanolic extract of Aerial parts of Hibiscus surattensis
The Study of volume and structure of sales of Pharmaceutical assortment of Antihypertensive drugs to 2019
Selecting a provider as the most important step in building a cold chain in Pharmaceutical Logistics
Formulation Development and Evaluation of Immediate release tablet of Terbinafine Hydrochloride
Evaluation of Metal levels and Physiological parameters in Sickle cell anemia and their comparison with Iron deficiency anemia
HPTLC and Antioxidant activity of Ethanolic Extract of Ipomoea obscura (L.) Ker Gawl Stem
Development, In-Vitro and In-Vivo Evaluation of Gastro Retentive Formulations for Moxifloxacin HCl
Effect of Steam Tomato Extract in Renal and Hepar Rats Loading Alloxan and Fat-Rich Diet
A Study to Identify any relationship between Hand dominance and restrictions in range of Motion in the protracted shoulder
Cytotoxic Potency of Bioactive Metabolites from an Endophytic Fungi Pestaloptiopsis breviseta against MCF-7 and A 549 Cancer cell lines

Tags


About Journal

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 4275
Yesterday: 21090
Total: 3703228