Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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In – vitro antioxidant activity of aqueous and ethanolic extract of Coscinium fenestratum root and Embelia ribes flower

Author(s): Basavaraj H, Purnima Ashok.

Email(s): basavarajhulkoti@gmail.com

DOI: Not Available

Address: Basavaraj H 1 , Purnima Ashok. 2
1Government College of Pharmacy, Bangalore.
2KLE University’s College of Pharmacy, Bangalore.
*Corresponding Author

Published In:   Volume - 5,      Issue - 4,     Year - 2012

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ABSTRACT:
The present study envisaged to evaluate in-vitro anti oxidant activity of ethanolic and aqueous extracts of roots of Coscinium fenestratum and extracts of Embelia ribes flower, by estimating nitric oxide scavenging activity, ferric thiocynate and total reduction capacity and carrying out DPPH assay of increasing concentration of extracts and compared with ascorbic acid, in view of investigations of pharmacological activities reported, extensive chemistry and being a part of folklore medicine. Review of literature revealed paucity of reports of in- vitro study of parts and extract chosen for the study. Results revealed concentration dependent increase in nitric oxide, DPPH free radical, ferric thiocyanate inhibition / scavenging activity, and similar total reduction capacity, indicated by increase in absorbance by ethanolic and aqueous extracts of roots of Coscinium fenestratum and of Embelia ribes flower. Ethanolic extracts possess relatively higher scavenging activity than aqueous extracts. The results identifies for the first time, the ethanolic and aqueous extracts of roots of Coscinium fenestratum and extracts of Embelia ribes flower, possess in-vitro antioxidant activity.


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Cite this article:
Basavaraj H, Purnima Ashok. In – vitro antioxidant activity of aqueous and ethanolic extract of Coscinium fenestratum root and Embelia ribes flower. Research J. Pharm. and Tech. 5(4): April 2012; Page 513-517.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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