Author(s): Katolkar P.P., Nimbekar T.P., Wanjari B.E., Nema M.V., Dongarwar A. S

Email(s): p_k_7995@yahoo.co.in

DOI: Not Available

Address: Katolkar P.P.*, Nimbekar T.P., Wanjari B.E., Nema M.V. and Dongarwar A. S.
Manoharbahi Patel Institute of Pharmacy (B. Pharm.), Kudwa, Gondia -441614
*Corresponding Author

Published In:   Volume - 5,      Issue - 4,     Year - 2012


ABSTRACT:
The main objective of the present work is to investigate the in vitro Anti-mitotic and Anti-proliferative activity of different extract of bark of Belanites aegyptiaca. The Anti-mitotic activity was screened using Allium cepa root meristamatic cells which have been used extensively in screening of drug with antimitotic activity using methotrexate as a standard. The anti-proliferative activity was screened using Yeast as a model system. The methanolic extract showed lowest mitotic index. Methanolic extract have maximum growth inhibition of yeast cells, growth inhibition increases as concentration of extract increases.


Cite this article:
Katolkar P.P., Nimbekar T.P., Wanjari B.E., Nema M.V., Dongarwar A. S. In-vitro antimitotic activity and antiproliferative activity of different extract of Belanites aegyptiaca. Research J. Pharm. and Tech. 5(4): April 2012; Page 474-477.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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