Katolkar P.P., Nimbekar T.P., Wanjari B.E., Nema M.V., Dongarwar A. S
Katolkar P.P.*, Nimbekar T.P., Wanjari B.E., Nema M.V. and Dongarwar A. S.
Manoharbahi Patel Institute of Pharmacy (B. Pharm.), Kudwa, Gondia -441614
Volume - 5,
Issue - 4,
Year - 2012
The main objective of the present work is to investigate the in vitro Anti-mitotic and Anti-proliferative activity of different extract of bark of Belanites aegyptiaca. The Anti-mitotic activity was screened using Allium cepa root meristamatic cells which have been used extensively in screening of drug with antimitotic activity using methotrexate as a standard. The anti-proliferative activity was screened using Yeast as a model system. The methanolic extract showed lowest mitotic index. Methanolic extract have maximum growth inhibition of yeast cells, growth inhibition increases as concentration of extract increases.
Cite this article:
Katolkar P.P., Nimbekar T.P., Wanjari B.E., Nema M.V., Dongarwar A. S. In-vitro antimitotic activity and antiproliferative activity of different extract of Belanites aegyptiaca. Research J. Pharm. and Tech. 5(4): April 2012; Page 474-477.