Author(s): M. Shakeera Banu, K. Sujatha, W. Sherly Beena, N. Divya

Email(s): sakeeramsb@gmail.com

DOI: Not Available

Address: M. Shakeera Banu1, K. Sujatha2, W. Sherly Beena3 and N. Divya4
1P.G. Department of Biotechnology, Sree Narayana Guru College, Coimbatore, Tamilnadu, India.
2P.G. and Research Department of Zoology, Governement Arts College, Tamilnadu, India. 3P.G. Department of Biochemistry, M.I.E.T. Arts and Science College,Tiruchirappalli, Tamilnadu, India.
4P.G. Department of Biochemistry, Pavendar Bharathidasan College of Arts and Science, Tiruchirappalli, Tamilnadu, India.
*Corresponding Author

Published In:   Volume - 5,      Issue - 4,     Year - 2012


ABSTRACT:
In diabetes, hyperglycaemia generates reactive oxygen species, which in turn cause lipid peroxidation and membrane damage and these free radicals play an important role in the production of secondary complications in diabetes. Wistar albino rats aged 6-8 week were selected for the experiments and these were divided into five groups. Diabetes was induced by alloxan. Blood glucose and hepatic antioxidant levels were measured. Psidium guajava and its isolated fraction restored the activities of antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx). It further decreased the hepatic lipid peroxidation as evidenced by decreased thiobarbituric acid reactive substances (TBARS) level with a concomitant increase in the reduced glutathione (GSH). Psidium guajava has a significant antihyperglycemic effect, and that this effect is associated with its antioxidative activity.


Cite this article:
M. Shakeera Banu, K. Sujatha, W. Sherly Beena, N. Divya. Antihyperglycemic and Antioxidant potentials Psidium guajava leaf extract and its isolated fraction in alloxan-induced diabetic rats. Research J. Pharm. and Tech. 5(4): April 2012; Page 541-546.


Recomonded Articles:

Author(s): P.Maheshwari, D.Pavithra, Neethu.T.T, T.S. Shanmugarajan, P. Shanmugasundaram

DOI: 10.5958/0974-360X.2017.00011.7         Access: Open Access Read More

Author(s): Santhosh Kumar V, Praveen D

DOI: 10.5958/0974-360X.2016.00123.2         Access: Open Access Read More

Author(s): Leelavathi D Acharya, N R Rau, N Udupa, Surulivel Rajan M, Vijayanarayana K

DOI: 10.5958/0974-360X.2016.00162.1         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): S. Subasree, Karthikeyan Murthykumar, Dhanraj

DOI: 10.5958/0974-360X.2016.00116.5         Access: Open Access Read More

Author(s): Vandana Gautam, Dhriti Kapoor, Saroj Arora, Renu Bhardwaj*

DOI: 10.5958/0974-360X.2016.00166.9         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Author(s): Deepak Karki, Gururaj S. Kulkarni, Shivakumar Swamy, Sheeba FR

DOI: 10.5958/0974-360X.2017.00750.8         Access: Open Access Read More

Author(s): S.M. Charjan, S.K. Bais, R.R. Shiradkar, R.L. Bakal, V.M. Durge, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Vaddi Mounika, S. Sarumathy, J. Anisha Ebens, T. S. Shanmugarajan

DOI: 10.5958/0974-360X.2017.00003.8         Access: Open Access Read More

Author(s): Rekha Rajendran, R Hemachander, T Ezhilarasan, C Keerthana, DL Saroja, KV Saichand, Mohamed Gasim Abdullah

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 


Recent Articles




Tags