Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Effects of Manilkara hexandra on blood glucose levels of normal and Alloxan induced diabetic rats

Author(s): NimbekarT.P., Katolkar P.P., Patil A.T.

Email(s): p_k_7995@yahoo.co.in

DOI: Not Available

Address: NimbekarT.P.1, Katolkar P.P.1* and Patil A.T.2
1Manoharbhai Patel Institute of (B. Pharm.) Pharmacy, Gondia. 441614.
2Department of Pharmaceutical Sciences, R.T.M. Nagpur University Nagpur. 440033.
*Corresponding Author

Published In:   Volume - 5,      Issue - 3,     Year - 2012

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ABSTRACT:
The dried bark of Manilkara hexandra is used traditionally, as an antidiabetic agent in India. To determine if there is a scientific basis for this use, the effects of the methanolic extracts on blood glucose levels were assessed in normoglycemic and alloxan induced diabetic rats. Blood glucose levels were evaluated at the intervals of 0, 1, 2, 3 and 6 h. Treatment of alloxan induced diabetic rats with Manilkara hexandra reduced glucose levels significantly and the extract is devoid of a significant hypoglycemic effect in normal rats. The finding of the present study in Manilkara hexandra lends credence to its folklore use in the management and/or control of type II diabetes.


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Cite this article:
NimbekarT.P., Katolkar P.P., Patil A.T. Effects of Manilkara hexandra on blood glucose levels of normal and Alloxan induced diabetic rats. Research J. Pharm. and Tech. 5(3): March 2012; Page 367-368.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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