Author(s): Naina Bhoyar, Tapan Kumar Giri, Amit Alexander, Dulal Krishna Tripathi, Ajazuddin

Email(s): write2ajaz@gmail.com

DOI: Not Available

Address: Naina Bhoyar, Tapan Kumar Giri, Amit Alexander, Dulal Krishna Tripathi and Ajazuddin*
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road Bhilai, Chhattisgarh, India
Corresponding author

Published In:   Volume - 5,      Issue - 2,     Year - 2012


ABSTRACT:
Tolnaftate (O-2-Naphthyl m, N-dimethylthiocarbanilate) is a topically used antifungal agent, most commonly employed in the treatment of tinea pedis at 1% (w/w) concentration. Analysis of this thionocarbamate fungicide which is also antidermatophytic, antitrichophytic and antimycotic agent primarily inhibits the ergosterol biosynthesis in the fungus. The spectra of Tolnaftate in methanol showed maximum wave length at 257nm and obeyed Beer’s law in the concentration range of 1-5 microgram/ml. Standard curve depict line equation y =0.148x-0.024 with correlation coefficient of 0.990. The developed method was validated with respect to linearity. The objective of present work is to develop simple, precise and accurate UV Spectrophotometric method for estimation of Tolnaftate in organic solvent. The organic solvent methanol is used was HPLC grade. This method can also be used for Tolnaftate determination in its marketed formulations.


Cite this article:
Naina Bhoyar, Tapan Kumar Giri, Amit Alexander, Dulal Krishna Tripathi, Ajazuddin. Development of UV Spectrophotometric Method for Qualitative and Quantitative Estimation of Tolnaftate in Different Formulations. Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 207-209.


Recomonded Articles:

Author(s): Umesh Kumar, Rakesh Narang, Surendra Kumar Nayak, Sachin Kumar Singh, Vivek Gupta

DOI: 10.5958/0974-360X.2017.00425.5         Access: Open Access Read More

Author(s): R. Narayana Charyulu, P. Parvathy Devi, Jobin Jose, A. Veena Shetty

DOI: Not Available         Access: Open Access Read More

Author(s): Dhanalekshmi UnniKrishnan Nair, MP Saraswathy, Narra Kishore, Neelakanta Reddy Pully

DOI: Not Available         Access: Open Access Read More

Author(s): Kumkum Sarangdevot, Bhawani Singh Sonigara, Amul Mishra, K. C. Gupta, Surbhi Sharma

DOI: Not Available         Access: Open Access Read More

Author(s): Hayat M. Mukhtar, Vandna Kalsi

DOI: 10.5958/0974-360X.2018.00395.5         Access: Open Access Read More

Author(s): Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan

DOI: Not Available         Access: Open Access Read More

Author(s): Adithya Chandrashekar, Anuraag Muralidharan, Ananthamurthy Koteshwara, Angel Treasa Alex, V. M. Subrahmanyam

DOI: 10.5958/0974-360X.2019.00791.1         Access: Open Access Read More

Author(s): Pankaj Kumar, Jennifer Fernandes, Abhishek Kumar

DOI: 10.5958/0974-360X.2017.00023.3         Access: Open Access Read More

Author(s): Pratik N. Shah, Bhavini N. Patel, Chaganbhai N. Patel

DOI: Not Available         Access: Open Access Read More

Author(s): Rajendra Jangde, S. J. Daharwal

DOI: Not Available         Access: Open Access Read More

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

Author(s): A. Khuntia, S.K. Mohanty

DOI: Not Available         Access: Open Access Read More

Author(s): Kumaraswamy G., J.M. Rajendrakumar, J.V.L.N. Sheshagirirao, U. Ashok Kumar, M. Arunadevi

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags