Analysis of phytochemical constituents and antimicrobial activity of plant extracts (Coffea arabica, Phyllanthus emblica and Terminalia chebula) were performed using various solvents (acetone, butanol, chloroform, hexane, methanol and water) against selected pathogenic microbes viz., Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeuroginosa, Salmonella typhi, Staphylococcus aureus, Aspergillus flavus, Aspergillus niger, Aspergillus parasiticus, Fusarium oxysporum and Fusarium verticilloides. Broad spectrum of antibacterial activity has been indicated in chloroform extracts of T. chebula against S. typhi (29 mm). Maximum inhibition has been found in methanol extracts against F. verticilloides (16 mm) and F. oxysporum (13 mm). Flavonoids condensed tannin and phenolic constituents was found to be fairly distributed in T. chebula. Therefore, T. chebula act as a potential source of antimicrobial agent.
Cite this article:
A. Rajeswari, S. Ramesh. Investigations on pharmacological constituent and antimicrobial efficacy of plant diffusate against clinical pathogens. Research J. Pharm. and Tech. 5(12): Dec. 2012; Page 1518-1524.