N. S. Devshetwar, L.V.G. Nargund, Nirmal T. Havannavar, Shachindra L. Nargund
N. S. Devshetwar1, L.V.G. Nargund1*, Nirmal T. Havannavar2, Shachindra L. Nargund3
1Department of Pharmaceutical Chemistry, Nargund College of Pharmacy, Dattatreya Nagar, II main,100Ft ring Road, BSK II stage, Bangalore- 560085 (India).
2Professor and Head, Dept. of Pharmaceutical Chemistry, MMU College of Pharmacy, Ramanagar.
3Dept of Chemistry, Texas State University, San Marco, USA.
Volume - 5,
Issue - 11,
Year - 2012
Indole containing organic compounds forms a significant class of drugs which exhibit an array of biological activities ranging from antibacterial, antifungal, anti-inflammatory, antipyretic to CNS depressants and anticancer. The present work aimed to synthesize novel 1-(6-Chloro-5-fluoro-3-phenyl-1H-indol-2-yl)-ethanone derivative with a desire to obtain potent antibacterial activity. The synthesized derivatives are characterized by Melting point, TLC, IR and 1H NMR spectra and then compounds are screened in-vitro antibacterial activity.
Cite this article:
N. S. Devshetwar, L.V.G. Nargund, Nirmal T. Havannavar, Shachindra L. Nargund. Synthesis of Substituted Fluoroindole as an Anti-Bacterial Agent. Research J. Pharm. and Tech. 5(11):November, 2012; Page 1446-1451.