Author(s): Syed Zia Ul Quasim1*, Abdul Naveed1, Shaik Ali Abbas1 and Mohd Abdul Irfan2

Email(s): Email ID Not Available

DOI: Not Available

Address: 1Dept. of Pharmaceutics, Deccan School of Pharmacy, Hyderabad 2Dept. of Pharmaceutics, Nizam college of Pharmacy, Hyderabad

Published In:   Volume - 5,      Issue - 10,     Year - 2012


ABSTRACT:
The present study was aimed at preparing a Floating drug delivery system for the model drug Rosuvastatin calcium, and evaluating the various processing parameters including the buoyancy studies and in vitro drug release studies. Four formulations containing varying proportions of polymers like HPMC K4M and Ethyl cellulose and fixed amount of gas generating agent such as Sodium bi carbonate and hydrophobic meltable material like bees wax were prepared. The tablets were prepared by melt granulation technique and the prepared tablets remained buoyant for more than 8hrs in the release medium. The proportions of the polymers showed significant difference in the release of the drug. All the formulations exhibited diffusion dominant drug release and were found to be stable.


Cite this article:
Not Available


Recomonded Articles:

Author(s): Ravi K. Barde, Minal R. Narkhede, V.R. Gudsoorkar, Rahul K. Amrutkar, Prashant S. Walke

DOI: Not Available         Access: Open Access Read More

Author(s): Katare Varsha B., Bhutkar M. A., Kumbhar A. P., Pol S. K., Katare P. B.

DOI: Not Available         Access: Open Access Read More

Author(s): Sajid Ali, Maryam Shabbir, Nabeel Shahid

DOI: 10.5958/0974-360X.2015.00019.0         Access: Open Access Read More

Author(s): Jayesh M Jain, Dinesh M Sakarkar, Shajahan Abdul, Mangesh E Bhad, Anil V Chandewar and Sunil B Jaiswal

DOI: Not Available         Access: Closed Access Read More

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Author(s): Gupalli Laxmi Narasimha, Dappu Jairam, Akkenapally Krishna, Mohammed Rehan Qureshi

DOI: 10.5958/0974-360X.2015.00025.6         Access: Open Access Read More

Author(s): K. Gnanaprakash, K.B. Chandhra Shekhar, C. Madhu Sudhana Chetty

DOI: Not Available         Access: Open Access Read More

Author(s): V. Swathi, G. Velrajan, Balasubramaniam

DOI: Not Available         Access: Open Access Read More

Author(s): Pare A, Yadav SK, Patil UK

DOI:         Access: Open Access Read More

Author(s): Thulasi V. Menon, C.I. Sajeeth

DOI: Not Available         Access: Open Access Read More

Author(s): Gupta Khemchand, Singhvi I., Ashawat M.S., Gupta Santosh Kumar

DOI: Not Available         Access: Open Access Read More

Author(s): Akbari BV, Dholakiya RB, Shiyani BG, Lodhiya DJ

DOI: Not Available         Access: Open Access Read More

Author(s): Kothawade PI, Zate SU, Gajbe JW, Rathi MN, Yewale CP, Baheti DR

DOI: Not Available         Access: Open Access Read More

Author(s): Maushumi Kulkarni, Rahul Thube, Kiran Bhise, Mohammed Kakajiwala

DOI: Not Available         Access: Open Access Read More

Author(s): Akelesh T., Sam Johnson, Udaya Chander J., Subhojit Samantha, Venkatanarayanan R.

DOI: 10.5958/0974-360X.2015.00268.1         Access: Open Access Read More

Author(s): Pavani M., D.P. Mastan Yadav, Manikanta Kumar A., K.S. Manjunath Shetty

DOI: Not Available         Access: Open Access Read More

Author(s): Ramesh V Shinde, Pawar Jaydip B, Kadam Sagar D, Landge Dhananjay A, Rahul Ahirrao, Kulkarni Vaishali , Patil VG, Pawar Gitanjali R

DOI: Not Available         Access: Open Access Read More

Author(s): Pankaj P. Ostwal, Yogesh L. Jadhav, Mayur S. Jain, Sumit P. Jain

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 


Recent Articles




Tags