A. Kaura, Lalit Sharma, V. J. Dhar
A. Kaura1*, Lalit Sharma2 and V. J. Dhar3
1University Institute of Pharmacy, Baba Farid University of Health Sciences, Faridkot.
2Dept. of Applied Chemistry, S.B.S. College of Engineering and Technology, Ferozepur.
3Swift School of Pharmacy, Ghaggar Sarai, Rajpura.
Volume - 5,
Issue - 1,
Year - 2012
In this report, synthesis and antimicrobial study of some Schiff bases and Beta-lactam derivatives has been reported. The synthesized Schiff bases and Beta-lactam derivatives were characterized by spectral data, including 1H-NMR, IR, Mass and Elemental analyses. All the compounds were screened for their in vitro antibacterial activity against two Gram +ve (Staphylococcus aureus, Bacillus subtilis) and two Gram –ve (Escherichia coli, Pseudomonas aeruginosa) bacterial strains by agar-well diffusion method. The Schiff bases were found to exhibit either no or low to moderate activity against one or more bacterial species. On contrary, all the Beta-lactam derivatives exhibited varied activity against different bacteria.
Cite this article:
A. Kaura, Lalit Sharma, V. J. Dhar. Spectral and Antimicrobial Study of Some Novel Schiff Bases and Beta-Lactam Derivatives. Research J. Pharm. and Tech. 5(1): Jan. 2012; Page 129-132.