Author(s): Arvind Kumar Gupta, Kawaljeet Kaur, Nawazish Alam, Sayeed Ahmad, Om Prakash Agarwal, Perwez Alam

Email(s): perwez_alam29@rediffmail.com

DOI: Not Available

Address: Arvind Kumar Gupta1, Kawaljeet Kaur1, Nawazish Alam2, Sayeed Ahmad3, Om Prakash Agarwal1 and Perwez Alam1*
1Natural Product Research Laboratory, Department of Pharmacognosy and Phytochemistry, SBS College of Pharmacy, Chuslewal Morh, Patti, (Tarn-Taran), Amritsar, Punjab-143416.
2 College of Pharmacy, Jazan University, Saudi Arabia.
3Natural Product Research Lab, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062
Corresponding author

Published In:   Volume - 5,      Issue - 1,     Year - 2012


ABSTRACT:
Boerhaavia diffusa Linn., belonging to family Nyctaginaceae, commonly known as “Punarnava”, is a perennial creeping herb, up to a height of 1-1.2 m. Parts of the plant have been used since long time in the treatment of various diseases. The roots have been reported to possess activities like diuretic, anti-inflammatory, laxative anthelmintic, stomachic, febrifuge, antileprosy, antiscabies, antiviral, and antitumour properties. In the present study, comparative standardization of the root of B. diffusa from two different geographical regions (Punjab and U.P) have been studied as per the WHO Guidelines to determine the correct identity and purity of the plant part and for the detection of adulteration as well. Botanical authentication and physicochemical parameters gave an idea about the quality of drug. The root powder was extracted with different solvents including Petroleum ether, Benzene, Chloroform, Ethyl acetate, Methanol and Water. Pharmacognostic study (macroscopic and powder microscopic) and physicochemical parameters (extractive values, ash values, foaming index, foreign matter, moisture content) were studied. The extractive values of hot extraction with methanol was found 15.3% w/w and 14.8%w/w and aqueous hot extractive was found 19.3%w/w and 19.7%w/w in Punjab and U.P. regions respectively. Total ash values were found 8.5%w/w and 9.15%w/w in Punjab and U.P. regions respectively. Further phytochemical screening revealed the presence of alkaloids, flavonoids, triterpenoids, phenolic compounds (tannins), saponins and steroids.


Cite this article:
Arvind Kumar Gupta, Kawaljeet Kaur, Nawazish Alam, Sayeed Ahmad, Om Prakash Agarwal, Perwez Alam. Comparative Standardization of Roots of Boerhaavia diffusa Linn. From Two Different Geographical Regions. Research J. Pharm. and Tech. 5(1): Jan. 2012; Page 114-118.


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