Mukesh Kumar D. J., Sonia K., Madhan R., Selvakumar K., Kalaichelvan P.T.
Mukesh Kumar D. J.1, Sonia K.2*, Madhan R.3, Selvakumar K. 3 and Kalaichelvan P.T.1
1 Centre for Advance Studies in Botany, University of Madras, Chennai, India
2Department of Biochemistry, Periyar University, Salem, India
3Department of Applied Biology and Nanobiosciences, BioLim Centre for Life Science, Chennai, India
Volume - 4,
Issue - 9,
Year - 2011
Ethanolic extracts of leaves, fruits and stem of Tribulus terrestris and leaves of Bougainvillea spectabilis were prepared and assessed for anti-yeast activity on Candida albicans and Malassezia furfur at 50 µl and 100 µl concentrations, compared with Fluconazole anti-yeast agent. The antioxidant activity was examined by various methods such as DPPH, ferrous ion reducing antioxidant power, ferrous ion chelating ability assay and cerium (IV) ion reducing power assay and compared with ascorbic acid, a-tocopherol, rutin and quercitin. The extracts were also evaluated for anticancer activity such as decatenation assay and catalytic activity assay and compared with KDNA. It was observed that the fruit of T. terrestris and leaves of B. spectabilis has flavanoid and saponin compounds by Thin layer chromatography. From the results, it is evident that ethanolic extract of fruit of T. terrestris and leaves of B. spectabilis has maximum anti-yeast activity against candida albicans at 100 µl concentration and has a potent antioxidant and anticancer activity.
Cite this article:
Mukesh Kumar D. J., Sonia K., Madhan R., Selvakumar K., Kalaichelvan P.T. Antiyeast, Antioxidant and Anticancer Activity of Tribulus terrestris Linn and Bougainvillea spectabilis Linn. Research J. Pharm. and Tech. 4(9): Sept. 2011; Page 1483-1489.