Author(s): Bhushan Pingale, Ravi Tiwari

Email(s): ravisun4@rediffmail.com

DOI: Not Available

Address: Bhushan Pingale and Ravi Tiwari*
SVKM’s NMIMS University, School of Pharmacy and Technology Management, Shirpur, Dist: Dhule,(MS)-425 405.
*Corresponding Author

Published In:   Volume - 4,      Issue - 9,     Year - 2011


ABSTRACT:
A rapid, simple and accurate RP-HPLC method was developed for the estimation of bupropion hydrochloride, using C18 column 250 x 4.6 mm i.d, 5 µm particle size in gradient mode, with mobile phase comprising of phosphate buffer (pH 4.0) and methanol. The flow rate was 1 mL min-1 and the detection wavelength was 252 nm. The retention time for bupropion hydrochloride was found to be 11.52 min. The proposed method was validated as per ICH (Q2R1) guideline with respect to the parameters viz., linearity, precision, accuracy, robustness, limit of detection and limit of quantification.


Cite this article:
Bhushan Pingale, Ravi Tiwari. Development and Validation of an RP-HPLC Method for the Estimation of Bupropion Hydrochloride. Research J. Pharm. and Tech. 4(9): Sept.2011; Page 1480-1482.


Recomonded Articles:

Author(s): A. S. K. Sankar, B. Datchayani, N. Balakumaran, Mohammed Rilwan, R. Subaranjani

DOI: 10.5958/0974-360X.2017.00047.6         Access: Open Access Read More

Author(s): Mukta D. Naykode, Durgacharan A. Bhagwat, Swapnil D. Jadhav, Harinath N. More

DOI: 10.5958/0974-360X.2017.00133.0         Access: Open Access Read More

Author(s): Mayanka Singh, Manoj Charde, Rajesh Shukla, Rita M. Charde

DOI: Not Available         Access: Open Access Read More

Author(s): YK Naidu, Raghunadha Reddy S, Koteswara Rao Divi, MP Kalyan Reddy, I Sarath Chandiran, KN Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Oruganti Sai Koushik, V. Himaja, P. Srinivasa Babu, Ramadoss Karthikeyan

DOI: 10.5958/0974-360X.2015.00298.X         Access: Open Access Read More

Author(s): Rituraj Singh Chundawat, Y.S. Sarangdevot, R.P.S. Rathore, Dharmendra Singh Sisodiya, Udaibhan Singh Rathore

DOI:         Access: Open Access Read More

Author(s): Vijaykumar T. Pawar, Shubhangi V. Pawar, Harinath N. More, Anita S. Kulkarni, Dinanath T. Gaikwad

DOI: 10.5958/0974-360X.2017.00724.7         Access: Open Access Read More

Author(s): Y Bhargava Reddy, C Jose Gnana Babu, KP Channabasavaraj, CH Sharada, V Reddy Panditi

DOI: Not Available         Access: Open Access Read More

Author(s): Mohamed Akram Melakhessou, Naima Benkiki, Salah Eddine Marref

DOI: 10.5958/0974-360X.2018.00952.6         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags