Author(s): R. Ramasubramania Raja, M. Niranjan Babu

Email(s): rsmr_raj@yahoo.co.in

DOI: Not Available

Address: R. Ramasubramania Raja* and M. Niranjan Babu
Department of Pharmacognosy, Seven Hills College of Pharmacy, Tirupati.
*Corresponding Author

Published In:   Volume - 4,      Issue - 7,     Year - 2011


ABSTRACT:
Ringworm is a skin infection caused by a fungus like trichiphyton rubrum and microsporum canis. Ringworm can affect skin on your body (Tinea corporis), scalp (Tinea capitis), groin area (Tinea cruris, also called jock itch), or feet (Tinea pedis, also called athlete's foot). Ringworm is a common skin disorder, especially among children, but it may affect people of all ages. Although its name suggests otherwise, it is caused by a fungus, not a worm. Ringworm occurs when a particular type of fungus grows and multiplies anywhere on your skin, scalp, or nails. Ringworm is contagious. It can be passed from one person to the next by direct skin-to-skin contact or by contact with contaminated items such as combs, unwashed clothing, and shower or pool surfaces. The fungi that cause ringworm thrive in warm, moist areas. Ringworm is more likely when you have frequent wetness (such as from sweating) and minor injuries to your skin, scalp, or nails. Antibiotics and other antimicrobial agents are effective in the prevention and treatment of ring worm, but they also cause undesirable side effects such as ecologic disturbance of oral and gut flora. Therefore, search for the anti fungal herbs could offer an effective alternative to antibiotic strategies for fungal infection disease like ring worm. The plant Aristolochia bracteolate Lam., was screened for its Macroscopic, Microscopic, Physiochemical parameter, Florescence analysis, General and microchemical analysis for crude powder and Plant cell inclusions. Qualitative and Total microbial load showed that they all within limit. Extraction was carried out by using soxhlet apparatus. Ethanolic extract effective against list out the fungal like Trichiophyton rubrum and Microsporum canis by Disc diffusion method. The Ethanolic extract of Arisolochia bracteolate Lam., showed highest activity at minimum concentration. Thus from our findings, it was concluded that the bioactive principles present in the extracts may be responsible in the treatment of ringworm infection. Developing countries like India having the percentage of poor people more, to meet with the demand of the poor public, the Aristolochia bracteolate Lam., may serve the purpose once the evaluation and detailed studies may over.


Cite this article:
R. Ramasubramania Raja, M. Niranjan Babu. Pharmacognostical Phytochemical and Antifungal Activity of Aristolochia bracteolate Lam., in Ringworm Infection. Research J. Pharm. and Tech. 4(7): July 2011; Page 1123-1128.


REFERENCE:

1.       Rashid, Rashid M., and Andrew C. Miller. "Tinea." (2009) eMedicine.

2.       Khandelwal K.R .Practical Pharmacognosy 19th Edition (2002)  P 24-25, 163-164

3.       Trease GE, Evans WC. Pharmacognosy, London; Bailiere Tindal;(1983)

4.       Harborne JB. A Guide to Modern techniques of plant Analysis.  USA:  Kluwer Academic Publishers; (1998)

 

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