Asthma is a clinical syndrome of unknown etiology characterized by three distinct components: (a) recurrent episodes of airway obstruction that resolve spontaneously or as a result of treatment: (b) exaggerated bronchoconstrictor response to stimuli that have little or no effect in nonasthmatic subjects, a phenomenon known as airway hyper responsiveness: and (c) inflammation of the airways as defined by a variety of criteria. Although airway obstruction is largely reversible, it is currently thought that changes in the asthmatic airway may be irreversible in some settings.1 The large burden it now imposes on patients, and the high health care costs have led to extensive research into its mechanisms and treatment.
Cite this article:
Naveen MR, Santhosh YL. Asthma: An Overview. Research J. Pharm. and Tech. 4(6): June 2011; Page 883-890.