Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Synthesis and Biological Activities of Some Novel Heterocyclic Compounds Containing Thiazolidinone Derivatives

Author(s): Puttaraj C., Chetan M. Bhalgat, Sandeep K. Chitale, B. Ramesh

Email(s): rambha¬_vin@yahoo.com

DOI: Not Available

Address: Puttaraj C., Chetan M. Bhalgat, Sandeep K. Chitale and B. Ramesh*
Department of Pharmaceutical Chemistry, S.A.C. College of Pharmacy, B.G.Nagara- 571448, Mandya.
*Corresponding Author

Published In:   Volume - 4,      Issue - 6,     Year - 2011

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ABSTRACT:
Amino group of thiazole moiety have been treated with various aromatic aldehydes gave corresponding Schiff's bases, 3A-G. These Schiff's bases have been reacted with thioglycolic acid, anhydrous zinc chloride and N,N'-dimethyl Formamide as a solvent to get corresponding novel thiazolidinone derivatives, 4A-G. Structures of all the newly synthesized compounds were confirmed by IR, 1H NMR, and mass spectral data. The synthesized compounds were evaluated for their antioxidant activity. Few compounds were found with potent antioxidant activity.


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Cite this article:
Puttaraj C., Chetan M. Bhalgat, Sandeep K. Chitale, B. Ramesh. Synthesis and Biological Activities of Some Novel Heterocyclic Compounds Containing Thiazolidinone Derivatives. Research J. Pharm. and Tech. 4(6): June 2011; Page 972-975.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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