Author(s): Ikewuchi Catherine C., Ikewuchi Jude C., Ayalogu Edward O., Onyeike Eugene N.

Email(s): ecoli240733@yahoo.com

DOI: Not Available

Address: Ikewuchi Catherine C., Ikewuchi Jude C.*, Ayalogu Edward O. and Onyeike Eugene N.
Dept. of Biochemistry, Faculty of Science, University of Port Harcourt, P.M.B. 5323, Choba, Rivers State, Nigeria
*Corresponding Author

Published In:   Volume - 4,      Issue - 5,     Year - 2011


ABSTRACT:
The effect of aqueous leaf extract of Sansevieria senegambica on the body and organ weights, plasma lipid profile and atherogenic indices of sub-chronic salt loaded rats were investigated. The control group received a diet consisting 100% of the commercial feed, while the four test groups received a diet consisting 8% salt and 92% commercial feed all through, except for the reference treatment group that had its salt-loading discontinued after six weeks. The extract was orally administered daily at 150 and 200mg/kg body weight; while the test control, reference and control groups received appropriate volumes of water by the same route. The extract significantly (P<0.05) lowered the weight gain, plasma total-, LDL- and non-HDL-cholesterol, compared to test control; and plasma triglyceride levels, compared to values before treatment, in the test animals. This result confirms the use of S. senegambica in the management of hypertension, and suggests that the extract may have a possible dose dependent protective mechanism against the development of atherosclerosis and cardiovascular complications.


Cite this article:
Ikewuchi Catherine C., Ikewuchi Jude C., Ayalogu Edward O., Onyeike Eugene N. Weight Reducing and Hypocholesterolaemic Effect of Aqueous Leaf Extract of Sansevieria senegambica Baker on Sub-Chronic Salt-Loaded Rats: Implication for the Reduction of Cardiovascular Risk. Research J. Pharm. and Tech. 4(5): May 2011; Page 725-729.


Recomonded Articles:

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Hayat M. Mukhtar, Vandna Kalsi

DOI: 10.5958/0974-360X.2018.00395.5         Access: Open Access Read More

Author(s): Swathy. S, Gheena. S, Sri Varsha. L

DOI: 10.5958/0974-360X.2015.00291.7         Access: Open Access Read More

Author(s): Kalaivanan S, Sarumathy S, Anisha Ebens J, Naresh Kumar K, Roobena Parveen A, Nasreen Ashraf M.

DOI: 10.5958/0974-360X.2017.00005.1         Access: Open Access Read More

Author(s): M U Uhumwangho, K Latha, S A Sunil, M V Srikanth, K V Ramana Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): R. Manikandan, A. Vijaya Anand

DOI: 10.5958/0974-360X.2015.00056.6         Access: Open Access Read More

Author(s): Roghith Kannan, Karpagam Krishnamoorthy

DOI: 10.5958/0974-360X.2016.00242.0         Access: Open Access Read More

Author(s): Santosh G Shep, Ashish B Roge, Nikhil M Mahajan, Atish R Sawant, Rupesh S Kamble, AV Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Michael Georgievich Grigoriev, Diana Konstantinovna Avdeeva

DOI: 10.5958/0974-360X.2017.00354.7         Access: Open Access Read More

Author(s): Preeti K. Suresh, Abhishek K. Sah, Sanjay J. Daharwal

DOI: Not Available         Access: Open Access Read More

Author(s): Abijeth. B, Mrs. Jothi Priya

DOI: Not Available         Access: Open Access Read More

Author(s): Ramesh V Shinde, Pawar Jaydip B, Kadam Sagar D, Landge Dhananjay A, Rahul Ahirrao, Kulkarni Vaishali , Patil VG, Pawar Gitanjali R

DOI: Not Available         Access: Open Access Read More

Author(s): Ram S Sakhare, Ashish B Roge, RL Bakal, MA Channawar, AV Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Mrs. C. Maheswari*, Dr. R.Venkatnarayanan, Mr. P. Babu, Mr. C.S. Kandasamy

DOI: Not Available         Access: Closed Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags