Author(s): Pradeep Kumar Samal, J.S. Dangi, Kedar Pd. Meena, N.R. Beck, Garima Maheshwari, Aswani Patel

Email(s): samalpharmacology@rediffmail.com

DOI: Not Available

Address: Pradeep Kumar Samal*, J.S. Dangi, Kedar Pd. Meena, N.R. Beck, Garima Maheshwari and Aswani Patel.
SLT. Institute of Pharmaceutical Sciences. Guru Ghasidas Vishwavidyalaya, Bilaspur ,Chhattisgarh.
*Corresponding Author

Published In:   Volume - 4,      Issue - 5,     Year - 2011


ABSTRACT:
The objective of this study was to investigate the hepatoprotective activity of Butea monosperma bark, against paracetamol induced hepatotoxicity. The Bark was dried in shade, powdered and Extracted with ethanol. Preliminary phytochemical analysis show the presence of phenolic compound and flavanoids. The ethanolic extract of Butea monosperma bark (EEBM) showed a significant dose dependent (250 mg and 500 mg/kg p.o. ) protective effect. The degree of protection was measured by using biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), total protein (TP), albumin(Alb) and total bilirubin (TB). The effects of EEBM was comparable to that of standard drug, Silymarin (25mg/kg). All the test drugs were administered orally by suspending in 0.5% of Tween 40 suspension.


Cite this article:
Pradeep Kumar Samal, J.S. Dangi, Kedar Pd. Meena, N.R. Beck, Garima Maheshwari, Aswani Patel. Hepatoprotective Activity of Butea monosperma bark on Liver Damage Caused by Paracetamol in Rats. Research J. Pharm. and Tech. 4(5): May 2011; Page 771-774.


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): Tarasankar Maity, Ayaz Ahmad, Nilanjan Pahari, Subarna Ganguli

DOI: Not Available         Access: Open Access Read More

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

Author(s): Jitendra Patel, A. Venkateshwar Reddy, G.S. Kumar, D. Satyasai4 B. Bajari, V. Nagarjuna

DOI: 10.5958/0974-360X.2017.00232.3         Access: Open Access Read More

Author(s): Subin Mary Zachariah, N. Aleykutty, Vidya Viswanad, Halima O.A.

DOI: Not Available         Access: Open Access Read More

Author(s): Hayat M. Mukhtar, Vandna Kalsi

DOI: 10.5958/0974-360X.2018.00395.5         Access: Open Access Read More

Author(s): Neha Rajput, Dinesh Sachan, Shikha Gangwar, Dipti Sachan

DOI: Not Available         Access: Open Access Read More

Author(s): Saba Shaikh, Ravi Dubey, Swati Dhande, Y.M Joshi, Vilasrao J. Kadam

DOI: Not Available         Access: Open Access Read More

Author(s): Poonam P. Patil, Mahesh M. Deshpande, Veena S. Kasture, Seema A. Gosavi

DOI:         Access: Open Access Read More

Author(s): Pankaj P. Ostwal, Yogesh L. Jadhav, Mayur S. Jain, Sumit P. Jain

DOI: Not Available         Access: Open Access Read More

Author(s): K. Hemalatha, K. Priya Darsini, D. Sunitha

DOI: Not Available         Access: Open Access Read More

Author(s): D. Benito Johnson, C.Senthil Kumar R. Rajesh, R. Venkatnarayanan, Mohammed Ansar VK

DOI: Not Available         Access: Open Access Read More

Author(s): Pradeep Kumar Samal

DOI: Not Available         Access: Open Access Read More

Author(s): Padmavathi D., Netravati Deshpande, Sarala A.

DOI: Not Available         Access: Open Access Read More

Author(s): Saher Mahmood Jwad, Bushra Abbas, Haider S. Jaffat

DOI: 10.5958/0974-360X.2015.00032.3         Access: Open Access Read More

Author(s): K. Hemalatha*, K. Priya Darsini and D. Sunitha

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags