Author(s): G. Gowtham, G. Ranjeeth Reddy, CH. Naveen kumar, R. Sathyanarayana, V.P. Pandey

Email(s): gowthamg540@gmail.com

DOI: Not Available

Address: G. Gowtham1*, G. Ranjeeth Reddy1, CH. Naveen kumar1, R. Sathyanarayana2 and V.P. Pandey2
1Pulla Reddy Institute of Pharmacy, Domadugu, Annaram, Medak (Dist), Andhra Pradesh, India.
2Department of Pharmacy, Annamalai University, Annamalai Nagar– 608 002, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 4,      Issue - 4,     Year - 2011


ABSTRACT:
The present study was designed to develop almotriptan tablets and invitro evaluation of almotriptan tablets, an anti-migraine drug. Since the innovator product Axert formula is being protected by IPR patent in connection with working formula, the efforts were made to develop with different process and different formula. In this study, the tablets were prepared by different formulations using sodium starch glycolate, povidone K-30, mannitol and MCC, based on trial and error basis. The compatibility of various excipients with the almotriptan was done using HPLC studies. The formulated tablets were subjected to evaluation for thickness, hardness, bulk density, tapped density, hausner ratio, compressibility index, stability studies and invitro release studies. The evaluated results of innovator physico-chemical parameters have been authorized as standard parameters for our new attempt of generic product development. The formulation F0809 showed the optimum evaluated parameters to that of the innovator and found to be stable under accelerated studies of temperature and humidity.


Cite this article:
G. Gowtham, G. Ranjeeth Reddy, CH. Naveen kumar, R. Sathyanarayana, V.P. Pandey. Formulation and Evaluation of Almotriptan Tablets. Research J. Pharm. and Tech. 4(4): April 2011; Page 533-536.


Recomonded Articles:

Author(s): Jino Elsa Thomas, Usha Y Nayak*, Jagadish PC, Koteshwara KB

DOI: 10.5958/0974-360X.2017.00007.5         Access: Open Access Read More

Author(s): Avinash Bhagwat, Suhas M Kakade, Chirag V Naval, Mukesh Tilker, Ravindra M Walture, Sagar A Adichwal and Atul P Chaudhari

DOI: Not Available         Access: Open Access Read More

Author(s): S.M. Charjan, S.K. Bais, R.R. Shiradkar, R.L. Bakal, V.M. Durge, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Rekha Kallam, Padma Sree K, Srinivas Arutla, MA Bari

DOI: Not Available         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Mohd Yousuf Ali, Md Shamim Qureshi, Md Hamed, Byasabhusan Das and K Purushotham Rao

DOI: Not Available         Access: Open Access Read More

Author(s): Krishnendu Acharya*, Somanjana Khatua, Salman Sahid

DOI: Not Available         Access: Open Access Read More

Author(s): Chandak BG, Sarpate RV, Chatterjee NR, Baheti KG

DOI: Not Available         Access: Open Access Read More

Author(s): Deependra Jain, Nishiprakash Jain, SK Jain, Nitin Jonwal, Shashank Mishra, Deepak Bhatt, Soham Shukla

DOI: Not Available         Access: Open Access Read More

Author(s): Karthikeyan D, Vijayakumar S, Pandey V.P, Nandha Kumar J, Sengottuvelu S, T. Sivakumar T.

DOI:         Access: Open Access Read More

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Author(s): S Hemalatha and M Jegadeesan

DOI: Not Available         Access: Closed Access Read More

Author(s): Poonam Karekar, Nitin Salunkhe, Adhikrao Yadav, Dnyaneshwar Bangar, Dhanashri Yadav

DOI: Not Available         Access: Open Access Read More

Author(s): Zain Mhanna, Wehad Ibrahim, Tamim Hammad

DOI: 10.5958/0974-360X.2016.00040.8         Access: Open Access Read More

Author(s): Anuradha A. Ranpise, Shilpa P. Chaudhari, Atul A. Phatak, Pratiksha M. Kadam

DOI: Not Available         Access: Open Access Read More

Author(s): Priti Patel, Ashok Kumar P., Hemil Shah, Nikunj Patel, Pratik Kheni, Someshwara Rao B., Suresh V. Kulkarni, Babitha S.

DOI: Not Available         Access: Open Access Read More

Author(s): Mettu Srikanth Reddy, Mallikarjun Setty

DOI: Not Available         Access: Open Access Read More

Author(s): Gupta Khemchand, Singhvi I., Ashawat M.S., Gupta Santosh Kumar

DOI: Not Available         Access: Open Access Read More

Author(s): Vijay Simha G.1, Meena Ajay Kumar1, Sannd Rajesh1, Panda P.2 and M.M. Rao3

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags