Author(s): Sheeba Rani M, Raja Sreekanth M, Emmanuel S

Email(s): emmanuelsj24@hotmail.com

DOI: Not Available

Address: Emmanuel S.*, Sheeba Rani M. and Raja Sreekanth M.
Dept. of Agricultural Science, Loyola Academy, Old Alwal, Secunderabad-500 010.
*Corresponding Author

Published In:   Volume - 4,      Issue - 3,     Year - 2011


ABSTRACT:
The present investigation was aimed at evaluating the wound healing potential of aerial parts and roots of Cleome viscosa Linn on albino Wistar rats. Excision and incision models were employed. In each wound model, male albino Wistar rats weighing 180-200g were divided into four groups of 6 animals each. In both the models, group I served as control and group II as reference standard treated with Soframycin. In an excision wound model, group III animals were treated with methanol extract of the aerial parts of C.viscosa (CVAMExt) 500 mg kg/ kg b.w and group IV animals were treated with methanol extract of the roots of C.viscosa (CVRMExt) 500 mg/ kg b.w, for 16 days respectively. In incision wound model, group III and IV animals were treated with CVAMExt and CVRMExt 500 mg/ kg b.w, for 9 days respectively. CVAMExt showed a 91.53% contraction in excision wounds, which was close to the contraction value of the reference drug Soframycin (100%). On the other hand, the same extract used on the incision wound model showed a significant increase (414.37±3.0) in wound tensile strength, which was almost similar to Soframycin. CVRMExt was also showed better wound healing activity in excision wound model 90.75% on day 16. Similarly the same extract used on the incision wound model also showed a better tensile strength (385.23±2.28). Enhanced wound contraction, skin breaking strength, decreased epithelialization time and histological characteristics suggest that extract C.viscosa may have therapeutic benefits in wound healing


Cite this article:
Sheeba Rani M, Raja Sreekanth M, Emmanuel S. Evaluation of the Wound-Healing Activity of Methanolic Extract of Cleome Viscosa Linn. Research J. Pharm. and Tech. 4(3): March 2011; Page 441-445.


Recomonded Articles:

Author(s): S. Subasree, Karthikeyan Murthykumar, Dhanraj

DOI: 10.5958/0974-360X.2016.00116.5         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Siripurapu Sriram, Venkata Ravibabu Mandla, Chaithanya Sudha M, Saladi S.V. Subba Rao, Nagaveni Ch, Vani V., Gobinath P., Raj Kumar KVG., Jaydeep Lella, Sannidhi Krishna Praveen, Debjit Datta

DOI: 10.5958/0974-360X.2017.00078.6         Access: Open Access Read More

Author(s): Ahmed Hilal Sheriff, Preetham Prasad Nittla

DOI: 10.5958/0974-360X.2019.00968.5         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Mahadeva Rao US, San San Oo, Nurul Liana Sabrin, Norsyahira Syazwana Mohd Razali, Khairunnisa Khalid, Nurul Farihah Mohamed Nadzari, Thant Zin

DOI: 10.5958/0974-360X.2017.00065.8         Access: Open Access Read More

Author(s): Mahanthesh M.C., Girendra Gautam, Jalalpure S.S.

DOI: 10.5958/0974-360X.2017.00250.5         Access: Open Access Read More

Author(s): Yarnykh T.G., Azarenko Iu. M., Buryak M.V., Bubilieva L. A.

DOI: 10.5958/0974-360X.2016.00115.3         Access: Open Access Read More

Author(s): Amutha K*, Ashok Kumar A, Godavari A

DOI: 10.5958/0974-360X.2017.00100.7         Access: Open Access Read More

Author(s): Krishnendu Acharya*, Somanjana Khatua, Salman Sahid

DOI: Not Available         Access: Open Access Read More

Author(s): Jayesh M Jain, Dinesh M Sakarkar, Shajahan Abdul, Mangesh E Bhad, Anil V Chandewar and Sunil B Jaiswal

DOI: Not Available         Access: Closed Access Read More

Author(s): Nur Qistina Binti Ahmad Fauzi, Vishnupriya V, Gayathri R.

DOI: 10.5958/0974-360X.2016.00240.7         Access: Open Access Read More

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Author(s): Oruganti Sai Koushik, V. Himaja, P. Srinivasa Babu, Ramadoss Karthikeyan

DOI: 10.5958/0974-360X.2015.00298.X         Access: Open Access Read More

Author(s): Jagdale Swati C., Hable Asawaree A., Kuchekar Bhanudas S., Chabukswar Aniruddha R.

DOI: Not Available         Access: Open Access Read More

Author(s): Manisha N. Trivedi, Archana Khemani, Urmila D. Vachhani, Charmi P. Shah, D.D. Santani

DOI: Not Available         Access: Open Access Read More

Author(s): J. Rubika

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags