Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)


Submit Article

A Validated RP-HPLC Method Development for Determination of Anthraquinone Marker from the Roots of Rubia cordifolia Linn.

Author(s): Khodke AS, Potale LV, Patole SM, Damle MC

Email(s): mcdamle@rediffmail.com

DOI: Not Available

Address: Khodke A.S., Potale L.V., Patole S.M., and Damle M.C.*
A.I.S.S.M.S. College of Pharmacy, Kennedy Road, Near R.T.O., Pune - 411 001.
*Corresponding Author

Published In:   Volume - 4,      Issue - 2,     Year - 2011

 View HTML        View PDF

ABSTRACT:
Herbal medicines have good efficacy, safety, and lesser side effects. They are in great in demand in developed world for primary health care. India has rich traditional knowledge, heritage of herbal medicines and large biodiversity but despite it India has dismal share of world market. Many Pharma companies market herbal preparation as neutraceutical and take excuses from quality control parameter set by W.H.O. India has thousands of medicinal plants but in Indian Pharmacopoeia, Quality Control parameter of only 56 plants are included. Rubia cordifolia Linn has good pharmacological activity. Both stem and roots of Rubia cordifolia Linn have pharmacological activity. But in I.P. 2007, marker designation for stem of Rubia cordifolia Linn is included. Hence we have developed and validated HPLC method for marker isolated from roots of Rubia cordifolia Linn. Marker was isolated from roots Rubia cordifolia Linn and purified. RP- HPLC method for marker was developed using mobile phase Methanol: water in the ratio of 80:20. Stationary phase used for this method was Hi-Qsil C18 (250 × 4.6mm i.d.). Using this mobile phase marker gets eluted at RT 4.294. This RP-HPLC method was validated as per ICH guideline.


Keywords:

Cite this article:
Khodke AS, Potale LV, Patole SM, Damle MC. A Validated RP-HPLC Method Development for Determination of Anthraquinone Marker from the Roots of Rubia cordifolia Linn. Research J. Pharm. and Tech. 4(2): February 2011; Page 326-328.


Recomonded Articles:

The Use of Neem in Oral Health

Author(s): Niha Naveed, Karthikeyan Murthykumar, Subasree Soundarajan, Sripradha Srinivasan

DOI: Not Available         Access: Open Access Read More

A review on pharmacological properties of Solanum tuberosum

Author(s): Koushika Das, Pranit Krishna, Avipsha Sarkar, Shanmuga Sundari Ilangovan, Shampa Sen

DOI: 10.5958/0974-360X.2017.00267.0         Access: Open Access Read More

Taxonomical, Phytochemical and Pharmacological Reviews of Musa sapientum var. Paradisiaca.

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Formulation and Evaluation of Mucoadhesive Buccal Tablets of Curcumin and its Bioavailability Study

Author(s): Deepak Karki, Gururaj S. Kulkarni, Shivakumar Swamy, Sheeba FR

DOI: 10.5958/0974-360X.2017.00750.8         Access: Open Access Read More

Formulation and Evaluation of Sustained Release Matrix Tablets of Pregabalin

Author(s): Katare Varsha B., Bhutkar M. A., Kumbhar A. P., Pol S. K., Katare P. B.

DOI: Not Available         Access: Open Access Read More

Project Writing for Retail Pharmacy Practical Training: A Proforma

Author(s): Prasad V. Patrekar, Sachin S. Mali

DOI: Not Available         Access: Open Access Read More

Formulation and Evaluation of Mouth Dissolving Tablets of Domperidone

Author(s): Avinash Bhagwat, Suhas M Kakade, Chirag V Naval, Mukesh Tilker, Ravindra M Walture, Sagar A Adichwal and Atul P Chaudhari

DOI: Not Available         Access: Open Access Read More

Formulation and Evaluation of Sustained Release Floating Matrix Tablets of Labetalol Hydrochloride.

Author(s): Ravi K. Barde, Minal R. Narkhede, V.R. Gudsoorkar, Rahul K. Amrutkar, Prashant S. Walke

DOI: Not Available         Access: Open Access Read More

Effect of Hesperidin for its Anti-Proliferative Activity on Liver Cancer and Cardio Vascular Diseases.

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Secondary Metabolite, Antioxidant, Phyto Nutrient Assay of Essential Oil from Dry Coriandrum sativum Seed Black Variety

Author(s): M. Krishnaveni, J. Santhoshkumar

DOI: 10.5958/0974-360X.2016.00161.X         Access: Open Access Read More

Formulation and Evaluation of Extended Release Matrix Formulation of Metoprolol Succinate

Author(s): Rekha Kallam, Padma Sree K, Srinivas Arutla, MA Bari

DOI: Not Available         Access: Open Access Read More

In-Vitro Study of Anthelmintic Activity of Eclipta prostrata (L) y various Extracts

Author(s): Kousalya M., Geetha P., Jesuraja A., Vinoth Kumar M

DOI: 10.5958/0974-360X.2017.00014.2         Access: Open Access Read More

Clinical Trial of Herbal Drugs and Products in India: Past and Current Status and Critical Issues

Author(s): Shrivastava Alankar, Jain R., Agrawal R.K., Ahirwar D.

DOI:         Access: Open Access Read More

Kumkuma the Social and religious marking of India is used as stain to improve the contrast of Pectinolytic actinomycetes VIT S2

Author(s): Suneetha V, Praveen Kumar G

DOI: 10.5958/0974-360X.2017.00229.3         Access: Open Access Read More

Concepts and Techniques of Pharmaceutical Powder Mixing Process: A Current Update

Author(s): R Deveswaran, S Bharath, BV Basavaraj, Sindhu Abraham, Sharon Furtado, V Madhavan

DOI:         Access: Open Access Read More

Synthesis and Antimicrobial Evaluation of Substituted Oxazolidinones Moieties

Author(s): Pankaj Kumar, Jennifer Fernandes, Abhishek Kumar

DOI: 10.5958/0974-360X.2017.00023.3         Access: Open Access Read More

Formulation and in vitro evaluation of gastroretentive drug delivery systems of amoxicillin trihydrate

Author(s): Mohammed Ehtesham Ur Rahman, Mohammed Abdul Haseeb, Mohammed Saleem, Abdul Naveed

DOI: Not Available         Access: Open Access Read More

Pharmacological Evaluation of Anti-Fertility Effect of Stem Bark of Ailanthus altissima in Wistar Albino Rats

Author(s): Munesh Mani, Devendra S. Rathore

DOI: 10.5958/0974-360X.2016.00092.5         Access: Open Access Read More

Formulation and Evaluation of Fast Dissolving Tablet of Telmisartan

Author(s): Priti Patel, Ashok Kumar P., Hemil Shah, Nikunj Patel, Pratik Kheni, Someshwara Rao B., Suresh V. Kulkarni, Babitha S.

DOI: Not Available         Access: Open Access Read More

Development and Evaluation of Sustained Release Matrix Tablets Using Natural Polymer as Release Modifier

Author(s): LP Hingmire, VN Deshmukh, DM Sakarkar

DOI:         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Quick Links

Latest Issues

Popular Articles


Recent Articles



Design, Synthesis, Characterization and Antioxidant activity of Novel Benzothiazole and Coumarin based 6-(3, 5-dimethylpyrazol-1-yl) pyridazin-3-one Derivatives
The Thermodynamic parameters of Chlorpromazine hydrochloride partitioning into Dimyrstoylphosphatidylcholine liposomes
The regulatory role of Neurotransmitters in Orexin B induced Nucleus Accumbens dependent alcohol ingestion in Wistar albino rats
Compounding practice in a developing Country: A Case study of divided Powder in Indonesia
Estimation of Anti-Diabetic property of Holarrhena pubescens by In Vitro method using L6 rat Skeletal Muscle Cell Lines
Synthesis, Spectral Characterization and Anticancer activity of Novel Pyrimidine Derivatives
Colon Specific Drug Delivery Systems – Different Systems and Approaches: A Review
Role of Dietary Supplements in Sports Performance
Bora Rice: Natural polysaccharide polymer for drug delivery
An outline on Curcumin: Its pro-liposome and Liposome Formulations
An Insight on pain modulation with Gender and Obesity: A Systematic Review
CNS and COVID-19: Neurological symptoms of Hospitalized Patients with Coronavirus in Iraq: a surveying case sequences study
Comparative Studies of the Amino acids profile Persicaria hydropiper L. Delarbre and Persicaria minor Hunds., growing in the Voronezh region (Russia)
Association of Leptin in Diabetes Mellitus and Obesity
Development and Evaluation of topical Emulgel of Aspirin using different Polymeric Bases
Formulation and Evaluation of Microemulsion containing Anti-Hypertensive Drug
Studying the prevalence of genital Chlamydia trachomatis IgG serum antibodies and associated risk factors in heterosexual men attending Tishreen University Hospital, Syria
Effect of Encapsulated Lactobacillus rhamnosus GG in Antibiotic associated diarrhea in Albino Wistar rat model
Pharmacognostic Evaluation and Standardization of the leaves of Mimosa pudica, leaves of Murraya koenigii and root of Asparagus racemosus
Quantitative Analysis of Combined Analgetic Tablets

Tags


About Journal

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 4564
Yesterday: 12610
Total: 5368362