Author(s): Nageshwar Rao Chilumula, Srinivas Ampati, Rajyalaxmi Gudipati, Sarangapani Manda, Dayakar Gaday

Email(s): profgdayakar@gmail.com

DOI: Not Available

Address: Nageshwar Rao Chilumula1, Srinivas Ampati2, Rajyalaxmi Gudipati2, Sarangapani Manda2 and Dayakar Gaday1*
1Departmet of Chemistry, Kakatiya University, Warangal, A.P-India, 506009
2University College of Pharmaceutical Sciences, Kakatiya University, Warangal, A.P.-India, 506009
*Corresponding Author

Published In:   Volume - 4,      Issue - 2,     Year - 2011


ABSTRACT:
A series of novel methyl-2-(arylideneamino)oxazol-4ylamino)benzoxazole-5-carboxylate derivatives synthesized. The structures of these compounds were established by IR, 1H NMR, 13C NMR, Mass spectral data and elemental analysis. Compounds were evaluated for their anti-inflammatory activity. Derivatives VIId and VIIe exhibited very good and almost equal anti-inflammatory activity in carrageenan-induced rat paw edema method compared with the standard drug Diclofenac Sodium.


Cite this article:
Nageshwar Rao Chilumula, Srinivas Ampati, Rajyalaxmi Gudipati, Sarangapani Manda, Dayakar Gaday. Design, Synthesis and Biological Evaluation of Methyl-2-(2-(Arylideneamino) Oxazol-4- Ylamino) Benzoxazole-5-Carboxylate Derivatives as New Antiinflammatory Agents. Research J. Pharm. and Tech. 4(2): February 2011; Page 302-307.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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