Author(s): Vishal Jain, Ambar Vyas, Swarnlata Saraf, S Saraf

Email(s): vj_rsofiop@rediffmail.com

DOI: Not Available

Address: Vishal Jain*, Ambar Vyas, Swarnlata Saraf and S. Saraf
Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (CG).
*Corresponding Author

Published In:   Volume - 4,      Issue - 2,     Year - 2011


ABSTRACT:
Quantification of active principles through modern analytical tools is essential for establishing the authenticity, creditability, prescription and usage of Ayurvedic medicines/herbal formulations. Triphala churna is one of the popular Ayurvedic preparations, official in Ayurvedic formulary of India. The present study is an attempt to develop a fingerprint method for Triphala churna with TLC Densitometric Methods (HPTLC) using gallic acid as a standard. The gallic acid is a major content in all the three ingredients of the formulation. The method was validated for linearity, accuracy, limit of detection, limit of quantification, inter-day and intra-day assay precision, repeatability of measurement, and repeatability of sample application. The concentration of gallic acid present in raw material was found to be 3.10±0.41% w/w in Emblica officinalis, 8.47±0.82% w/w in Terminalia belerica, and 4.63±0.49% w/w in Terminalia chebula. Gallic acid content in three identical laboratory batch of Triphala churna TP-I, TP-II and TP-III, was found to be 5.39±0.48%, 5.42±0.46% and 5.41±0.52% w/w respectively with mean value 5.41±0.49%. The gallic acid content in all the three different batches is found to be in close proximities with each other. The results were comparable to marketed formulations.


Cite this article:
Vishal Jain, Ambar Vyas, Swarnlata Saraf, S Saraf. TLC Densitometric Methods for Quantification of Gallic Acid in Triphala Churna for Routine Quality Control. Research J. Pharm. and Tech. 4(2): February 2011; Page 230-233.


Recomonded Articles:

Author(s): A. S. K. Sankar, B. Datchayani, N. Balakumaran, Mohammed Rilwan, R. Subaranjani

DOI: 10.5958/0974-360X.2017.00047.6         Access: Open Access Read More

Author(s): Mukta D. Naykode, Durgacharan A. Bhagwat, Swapnil D. Jadhav, Harinath N. More

DOI: 10.5958/0974-360X.2017.00133.0         Access: Open Access Read More

Author(s): Mayanka Singh, Manoj Charde, Rajesh Shukla, Rita M. Charde

DOI: Not Available         Access: Open Access Read More

Author(s): YK Naidu, Raghunadha Reddy S, Koteswara Rao Divi, MP Kalyan Reddy, I Sarath Chandiran, KN Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): Oruganti Sai Koushik, V. Himaja, P. Srinivasa Babu, Ramadoss Karthikeyan

DOI: 10.5958/0974-360X.2015.00298.X         Access: Open Access Read More

Author(s): Bulusu Ravi Teja, Bhupathi Raju Kishan Varma, Chandaka Prasanna Kumar, Mukthinuthalapati Mathrusri Annapurna

DOI: 10.5958/0974-360X.2017.00206.2         Access: Open Access Read More

Author(s): Mohamed Akram Melakhessou, Naima Benkiki, Salah Eddine Marref

DOI: 10.5958/0974-360X.2018.00952.6         Access: Open Access Read More

Author(s): T. Sheela Rani, V. Gopal, S. Seethalakshmi, K. Chitra

DOI: Not Available         Access: Open Access Read More

Author(s): Garima Singh, Amrita Mishra, Anurag Verma, Arun K. Mishra

DOI: Not Available         Access: Open Access Read More

Author(s): Anuruddha R. Chabukswar, Shital D. Tambe, Vishnu P. Choudhari, Shailesh N. Sharma, Mayuri N. Mohokar, Subhash Chate

DOI: Not Available         Access: Open Access Read More

Author(s): Arun Shirwaikar, Sarala Devi, K Premalatha, Muhammed Maqbool, Sreejith K.R.

DOI: Not Available         Access: Open Access Read More

Author(s): B. Mohammed Ishaq, V.S. Thiruvengada Rajan, S. Angala Parameswari, N. Amruth, M. Madhu, C. Madhusudana Chetty

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags