Author(s): Pachoriya R, Sharma A

Email(s): rahul_pachoriya@yahoo.co.in

DOI: Not Available

Address: Pachoriya R and Sharma A
Department of Pharmaceutics, V.N.S Institute of Pharmacy, Neelbud, Bhopal (M.P.) India
*Corresponding Author

Published In:   Volume - 4,      Issue - 2,     Year - 2011


ABSTRACT:
As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. Pulmonary delivery of macromolecule provides direct access to disease in the treatment of respiratory diseases, while providing an enormous surface area and a relatively low enzymatic, controlled environment for systemic absorption of medication. Macromolecular Porous microparticle possess densities sufficient small to create aerodynamic particle sizes in the range of 1-5 µm, and for deep lung delivery 1-3 µm. To impart favorable aerodynamic properties, an effervescent technology provides encapsulate drug efficiently, sustained drug release, create porous scaffold for tissue engineering application.


Cite this article:
Pachoriya R, Sharma A. New Technologies in Particulate Engineering for Pulmonary Delivery of Macromolecule. Research J. Pharm. and Tech. 4(2): February 2011; Page 167-174.


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DOI: 10.5958/0974-360X 

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