Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method

Hemlata M. Nimje; Rajesh J. Oswal; Sandip S. Kshirsagar; Manoj Chavan

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method

Author(s): Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan

Email(s): hemanimje@gmail.com

DOI: Not Available

Address: Hemlata M. Nimje*, Rajesh J. Oswal, Sandip S. Kshirsagar and Manoj Chavan
JSPM’s Charak College of Pharmacy and Research, Pune-Nagar Road, Wagholi, Pune-412 207
Corresponding author:

Published In: Volume - 4, Issue - 12, Year - 2011

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ABSTRACT:
A simple, rapid and accurate spectrophotometric method has been developed for quantitative estimation of felodipine in bulk and tablet. Felodipine is a long-acting calcium channel blocker (dihydropyridine class) used as an anti-hypertensive and in the treatment of angina. In methanol felodipine exhibits absorption at 362.4 nm and method obeys Beer’s law at the concentration range of 10-100 µg/mL. The percentage label claim was found in the range of 98-103%. The proposed method was validated statistically and recovery studies.

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Cite this article:
Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan. Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1805-1806.

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