Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method

Hemlata M. Nimje; Rajesh J. Oswal; Sandip S. Kshirsagar; Manoj Chavan

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

Submit Article

Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method

Author(s): Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan

Email(s): hemanimje@gmail.com

DOI: Not Available

Address: Hemlata M. Nimje*, Rajesh J. Oswal, Sandip S. Kshirsagar and Manoj Chavan
JSPM’s Charak College of Pharmacy and Research, Pune-Nagar Road, Wagholi, Pune-412 207
Corresponding author:

Published In: Volume - 4, Issue - 12, Year - 2011

View HTML

View PDF

ABSTRACT:
A simple, rapid and accurate spectrophotometric method has been developed for quantitative estimation of felodipine in bulk and tablet. Felodipine is a long-acting calcium channel blocker (dihydropyridine class) used as an anti-hypertensive and in the treatment of angina. In methanol felodipine exhibits absorption at 362.4 nm and method obeys Beer’s law at the concentration range of 10-100 µg/mL. The percentage label claim was found in the range of 98-103%. The proposed method was validated statistically and recovery studies.

Keywords:

Cite this article:
Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan. Spectrophotometric Analysis for Estimation of Felodipine in Tablet Dosage Form by Calibration Curve Method. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1805-1806.

Recomonded Articles:

Analytical method development and validation of ambroxol hydrochloride by UV spectroscopy and forced degradation study and detection of stability.

Author(s): M. Sumithra, P. Yuvanesh, Anamika Mistry

DOI: 10.5958/0974-360X.2016.00152.9 Access: Open Access Read More

A comparative, Bioequivalence study to evaluate the safety and pharmacokinetic profile of single dose Ivabradine 7.5mg Tablets in healthy, adult, human subjects under fasting condition.

Author(s): Amol K Choulwar, Ashish A. Mungantiwar, Meena Chintamaneni

DOI: Not Available Access: Open Access Read More

A Mini-Review of Spectrophotometric and Chromatographic Analysis and Bioanalysis of Selected Recently Approved Anti-Diabetic Combinations

Author(s): Maha F. Abdel-Ghany, Miriam F. Ayad, Mariam M. Tadros

DOI: 10.5958/0974-360X.2017.00563.7 Access: Open Access Read More

Formulation and Evaluation of Aspirin Tablets by Using Different Lubricants in Combination for better Kinetic Drug Release Study by PCP

Author(s): Pawan Singh, Prevesh Kumar, Neelkant Prasad

DOI: 10.5958/0974-360X.2017.00519.4 Access: Open Access Read More

Design and Evaluation of Nimesulide Lozenges for Pediatrics

Author(s): Mohd Yousuf Ali, Md Shamim Qureshi, Md Hamed, Byasabhusan Das and K Purushotham Rao

DOI: Not Available Access: Open Access Read More

Method Development and Validation of Fingolimod in Bulk and Tablet Dosage Form by RP-HPLC

Author(s): Murugan S, Chandra Sekhar R

DOI: 10.5958/0974-360X.2017.00456.5 Access: Open Access Read More

Analytical Method Development and Validation for the Determination of Allopurinol and Alphalipoic Acid Using Reverse Phase HPLC Method in Bulk and Tablet Dosage Form

Author(s): R. Vani, B. Vijaya Kumar, G. Krishna Mohan

DOI: 10.5958/0974-360X.2015.00038.4 Access: Open Access Read More

Formulation and Characterization of Taste Masked Rapid Disintegrating Tablets of Trimetazidine HCl

Author(s): Barokar A.A., Wagh R.D., Baviskar D.T., Shaikh T.J.

DOI: Not Available Access: Open Access Read More