Author(s): MP Yeole, A J Asnani

Email(s): mp¬_yeole@rediffmail.com

DOI: Not Available

Address: M.P. Yeole* and A. J. Asnani
J. L. Chaturvedi College of Pharmacy, Electronic zone, MIDC, Hingana, Nagpur-16
*Corresponding Author

Published In:   Volume - 4,      Issue - 1,     Year - 2011


ABSTRACT:
A simple, sensitive and accurate RP-HPLC method has been developed and subsequently validated for simultaneous determination of telmisartan and amlodipine besylate. The separation was carried out by using mobile phase consisting of acetonitrile, methanol and phosphate buffer pH4.5 in the ratio (15:35:50) v/v and adjusted pH±0.1 with phosphoric acid. The column used was SS Wakosil-II C-18 with flow rate of 1ml/min and UV detection at 255nm. The described method was linear over a concentration range of 10.0-400µg/ml and 1-80µg/ml for the assay of telmisartan and amlodipine besylate respectively .The mean percentage recoveries obtained for telmisartan was 98.2% and for amlodipine besylate 99.5% when determined at five different levels. The proposed method is precise, accurate, selective and rapid for the simultaneous determination of telmisartan and amlodipine besylate-


Cite this article:
MP Yeole, A J Asnani. Simultaneous Determination of Telmisartan and Amlodipine in Tablets by Reverse Phase High Performance Liquid Chromatography. Research J. Pharm. and Tech. 4 (1): January 2011; Page 75-77.

Cite(Electronic):
MP Yeole, A J Asnani. Simultaneous Determination of Telmisartan and Amlodipine in Tablets by Reverse Phase High Performance Liquid Chromatography. Research J. Pharm. and Tech. 4 (1): January 2011; Page 75-77.   Available on: https://rjptonline.org/AbstractView.aspx?PID=2011-4-1-6


Recomonded Articles:

Author(s): Rakhi Mehra, Renu Makhija, Neera Vyas

DOI: Not Available         Access: Open Access Read More

Author(s): A. S. K. Sankar, B. Datchayani, N. Balakumaran, Mohammed Rilwan, R. Subaranjani

DOI: 10.5958/0974-360X.2017.00047.6         Access: Open Access Read More

Author(s): Peethala Prathyusha, Raja Sundararajan, Palyam Bhanu, Mathrusri Annapurna Mukthinuthalapati

DOI: 10.5958/0974-360X.2020.00507.7         Access: Open Access Read More

Author(s): Naveen M.R., Santhosh Y.L., Satish Kumar B.P

DOI: Not Available         Access: Open Access Read More

Author(s): Rekha Rajendran, R Hemachander, T Ezhilarasan, C Keerthana, DL Saroja, KV Saichand, Mohamed Gasim Abdullah

DOI: Not Available         Access: Open Access Read More

Author(s): Sonte Sushmitha, Sedimbi Revathi Priyanka, L. Mohan Krishna, M. Srinavasa Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Diksha Sharma, Dinesh Kumar Mehta, Karun Bhatti, Rina Das, Ram Mohan Chidurala

DOI: 10.5958/0974-360X.2020.00532.6         Access: Open Access Read More

Author(s): Rupali Deshmukh, Roshni Agrawal, Sarita Chauragde, Swati Lilhare, M. U. Mishra

DOI: 10.5958/0974-360X.2018.00831.4         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Muhammad Hamdan, Noorhamdani AS, Masruroh Rahayu, Mohammmad Hasan Machfoed

DOI: 10.5958/0974-360X.2019.01020.5         Access: Open Access Read More

Author(s): Martin Ebenezer. C, Goh C.X.H, Jemeela. S, Manoj Abraham. M, Jabbar. M. S

DOI: 10.5958/0974-360X.2019.00283.X         Access: Open Access Read More

Author(s): Mohd Yousuf Ali, Md Shamim Qureshi, Md Hamed, Byasabhusan Das and K Purushotham Rao

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags