Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)


Submit Article

Anti-Ulcer Activity of Crude Alcoholic Extract of Rhizomes of Cissus repens Lan.

Author(s): Umbare RP, Mate GS, Dongare SS

Email(s): ramumbare1402@gmail.com , ramumbare1402@rediffmail.com

DOI: Not Available

Address: Umbare R.P.*, Mate G.S. and Dongare S.S.
A.S.P.M’s K.T. Patil College of Pharmacy, Siddharth Nagar, Barshi Road, Osmanabad, (M.S.), India- 413501.
*Corresponding Author

Published In:   Volume - 4,      Issue - 1,     Year - 2011

 View HTML        View PDF

ABSTRACT:
The present study was designed to evaluate the effects of ethanol extract of Cissus repens Lan against experimentally induced gastric ulcers. It is evaluated for its anti-ulcer activity against aspirin plus pylorus ligation induced gastric ulcer (antisecretory), HCl–ethanol induced ulcer (cytoprotective) and water immersion stress induced ulcer in rats. We found that Cissus repens Lan extract at a dose of 300 mg/kg p.o. markedly decrease the incidence of ulcers in all the three models. Ethanol extract of Cissus repens Lan showed significant reduction in gastric volume, free acidity, total acidity and ulcer index. The plant extract also showed gastro protective activity (49.65%), whereas standard drug sucralfate showed 90.49%. Cissus repens Lan extract showed protection index 39.0% in water immersion stress induced ulcer, whereas standard drug omeprazole showed protection index 98%.


Keywords:

Cite this article:
Umbare RP, Mate GS, Dongare SS. Anti-Ulcer Activity of Crude Alcoholic Extract of Rhizomes of Cissus repens Lan. Research J. Pharm. and Tech. 4 (1): January 2011; Page 60-62.


Recomonded Articles:

Removal of basic dye from synthetic wastewater using sugarcane bagasse modified with propionic acid

Author(s): Sandra Sajen, Jephin Varughese Jose, Sandeep Bukke, Chaithanya Sudha M, Saladi S.V. Subbarao, V.R. Mandla

DOI: 10.5958/0974-360X.2017.00286.4         Access: Open Access Read More

Anti-Ulcer Activity of Crude Alcoholic Extract of Rhizomes of Cissus repens Lan.

Author(s): Umbare RP, Mate GS, Dongare SS

DOI: Not Available         Access: Open Access Read More

Anti-Depressant Activity of Ethanolic Extract of Citrullus vulgaris Seeds in Experimentally Induced Depressed Mice

Author(s): R. S. Adnaik, P. S. Gavarkar, S. K. Mohite, C, S Magdum

DOI: Not Available         Access: Open Access Read More

Preparation and Evaluation of Mucoadhesive Microspheres Containing Heparin for Antiulcer Therapy

Author(s): Venkateswaramurthy N, Sambathkumar R, Vijayabaskaran M, Perumal P

DOI: Not Available         Access: Open Access Read More

Antiulcer Activity of Leaf Extract of Lawsonia inermis in Albino rats

Author(s): Venkateshwarlu Goli, Sravan Prasad Macharla, K. Vijaya Bhasker, N.L Gowrishankar, J. Bhaskar, Ch. Dhanalakshmi

DOI: Not Available         Access: Open Access Read More

Evaluation of the Effect of Quercus infectoria Olivier (Fagaceae) in Experimentally Induced Inflammatory Bowel Disease in Rats.

Author(s): Roshni P. Solanki, Tejal R. Gandhi, Kirti V. Patel.

DOI: Not Available         Access: Open Access Read More

Gastro Protective effect of Standardized Ethanolic leaf extract of Indigofera tinctoriao on experimental Gastric Ulcers in Rats

Author(s): P. Manimekalai, P. Maheshwari, R. Velmurugan, M. Gurumoorthy, S. Hansraj Kumar, G. Vijayakumar

DOI: 10.5958/0974-360X.2018.00098.7         Access: Open Access Read More

Preclinical Evaluation of Antiulcer activity of hydroalcoholic extracts of Macrotyloma uniflorum seed

Author(s): Samarjit Bose, Mrityunjoy Majumdar

DOI: 10.5958/0974-360X.2020.00161.4         Access: Closed Access Read More

Investigation on Graphene Nanofluids and its Applications: A brief Literature Review

Author(s): S. Suneetha, P. Bala Anki Reddy

DOI: 10.5958/0974-360X.2016.00124.4         Access: Open Access Read More

Evaluation of Wound Healing and Anti Microbial Activity of the Argemone mexicana Linn (Papavraceae)

Author(s): Saravanan. R, Senthilkumar. K., Dhachinamoorthi. D., Uma Mahesh. P, Vamsi Krishna. G, Venkata Pavani. K

DOI: 10.5958/0974-360X.2017.00159.7         Access: Open Access Read More

A Study on the Effect of Centella asiatica on Experimentally Induced Inflammatory Bowel Disease in Albino Rats.

Author(s): Mangala Lahkar, Pradumna Pathak

DOI: Not Available         Access: Open Access Read More

Evaluation of Leaf extracts of Simarouba glauca on Experimentally Induced Inflammatory Bowel Diseases in Wistar rats

Author(s): G. Ariharasivakumar, T. Karthikaa, Ridahunlang Nongkhlaw, P. Packialakshmi

DOI: 10.5958/0974-360X.2020.00340.6         Access: Closed Access Read More

Potential activity of Madhuca longifolia leaf extract: through In vitro, Pharmacological and In silico studies

Author(s): Jerine Peter S, Ram Kumar K, Manisha P, Sangeetha N, Arun Raj N, Usha Kumari, Evan Prince Sabina

DOI: 10.5958/0974-360X.2020.00199.7         Access: Closed Access Read More

Evaluation of the Effect of Quercus infectoria Olivier (Fagaceae) in Experimentally Induced Inflammatory Bowel Disease in Rats.

Author(s): Roshni P. Solanki, Tejal R. Gandhi, Kirti V. Patel.

DOI: Not Available         Access: Open Access Read More

Simultaneous Spectrophotometric Estimation of Lornoxicam and Thiocolchicoside in Combined Dosage Form

Author(s): Madhusmita Sahoo, Pratima K Syal, Snehal S Ingale, Dipali M Mehetre, Vishnu P Choudhari, Bhanudas S Kuchekar

DOI: Not Available         Access: Open Access Read More

Antiulcer Activity of Methanol Extract of Leaves of Bauhinia racemosa Linn (Leguminaceae)

Author(s): Rasika D Bhalke, Mahendra A Giri, Subodh C Pal

DOI: Not Available         Access: Open Access Read More

Effect of Cuscuta reflexa extract on Experimentally Induced Hypertension in normal and Streptozotocin Induced Diabetes in Rats

Author(s): G. B. Jadhav, R. R. Bhure, K. N. Mundlod, A. P. Pingle

DOI: 10.5958/0974-360X.2020.00249.8         Access: Closed Access Read More

Gastroprotective Effect of Lannea coromandelica Stem Bark in Rat induced by Aspirin

Author(s): Jastria Pusmarani, Mus Ifaya, Muhammad Isrul, Ahmad Saleh, Himaniarwati

DOI: 10.5958/0974-360X.2019.00275.0         Access: Open Access Read More

Antiulcer and Analgesic Activity of the Ethanol Extract of Cleome gynandra Linn Leaves.

Author(s): KK Sivakumar, A Rajasekaran, I Ponnilavarasan, A Somasundaram, R Sivasakthi, Kamalaveni

DOI: Not Available         Access: Open Access Read More

Optimization of Process Parameters for Total Phenol Extraction from Wood Waste using Response Surface Methodology

Author(s): R. Subbaiya, V. Vijay Raja, R. Balachandar, D. Suresh, S. Chozhavendhan, S. Vinoth, G. Karthiga Devi

DOI: 10.5958/0974-360X.2019.00180.X         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Quick Links

Latest Issues

Popular Articles


Recent Articles



Analytical Method development and Validation of Teneligliptin by RP-UFLC
A Modified Method to Determine Lipids Peroxidation in patients with HPV16 Cervicitis
Pharmacokinetic Modifications of Immediate release tablets of Raloxifene Hydrochloride by hot melt Technology
Formulation and Evaluation of Gastro Retentive Floating Tablets of Ritonavir
Evaluation of haematological changes in Entamoeba histolytica-infected rats administered with extracts of Ziziphus mauritiana leaves
Optimization of xylanase production from penicillium funiculosum using agricultural (Corn cob) waste
In vivo Study of Insulin-loaded Microemulsion Topical gel with Aloe vera for the Treatment of Dermatologic Manifestation of Diabetes
Effect of Vitamin D supplement on the risks of Cardiovascular disease in patients with type 2 diabetes in the Kurdistan Region of Iraq
Use of inhaler device in patients with Asthma or Chronic obstructive pulmonary disease: Errors and Adherence problems
Homology modeling of microbial Nattokinase enzyme, An Anti-blood clotting (Fibrinolytic) agent using computational tools
Optimization and Characterization of Lipid Based Nano Emulsion of Prednisolone Acetate for Ophthalmic Drug Delivery
Neuroprotective Potency of Tamarindus indica Seed Extract for Preventing Memory Impairment in Rat Model of Alzheimer
Preparation and Evaluation of Nifedipine solid dispersions
Evaluation of Anti-cancer, Antioxidant and Antimicrobial Activities of Alstonia scholaris L
Methanol and Ethyl Acetate Extracts of Red Fruit (Pandanus conoideus Lam.) Short-Red showed high of Phenolic and Radicals Scavenging Activities
Biological activity of Simarouba amara (Aubl.) bark
An Insilico Pharmacological Evaluation of Saraswatharishtam for Alzheimer’s disease - An Ayurvedic Formulation
Utility of Maxilla-mandibular indices for gender determination by using lateral cephalograms
The knowledge and views of Indian researchers concerning India’s current drugs and clinical trial regulations
Formulation Development and In vitro Characterization of solid lipid Nanoparticles of Felbamate

Tags


About Journal

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 2384
Yesterday: 19178
Total: 3251939