ABSTRACT:
From the results, it shows that there was no significant changes (P>0.05) compared with the control in the consumption of the contaminated diet with pestox insect powder indicating that the increased concentration of pestox insect powder did not significantly (P>0.05) affect the palatability of the diet. The results showed that the animals (rats) gained weight, the contamination of the diet with pestox insect powder notwithstanding. The result also showed that there was significant increase (P<0.05) in the level of AST activity with the increased concentration of contaminated diet of pestox insect powder from 1% to 15% via each week of both male and female albino rats. The ALT activities in various groups of the rats each week showed significant difference (P<0.05) in the serum when compared with the control groups. The results for each week for both male and female rats showed significant increase (P<0.05) in the level of total protein of other groups compared to the different controls for each week. The serum lipid peroxidation in both the male/female was not significant (P>0.05) in the 1st and 2nd week compared with the 3rd week where there was significant difference (P<0.05) between the control group and 1%, 5%, 10% and 15% contamination groups. The experimental results suggested that the level of toxicity of pestox insect powder depends on the level of exposure in respect to various concentrations and time dependent.