Author(s): Chandak BG, Sarpate RV, Chatterjee NR, Baheti KG

Email(s): badri_chandak30@yahoo.co.in

DOI: Not Available

Address: Chandak B.G.1*, Sarpate R.V.1 , Chatterjee N.R.2 and Baheti K.G.2
1Siddhant College of Pharmacy, Sudumbare, Pune. 2Department of Pharmaceutical Chemistry, Pad Dr. D.Y. P. College of Pharmacy, Akurdi, Pune-411044
*Corresponding Author

Published In:   Volume - 3,      Issue - 3,     Year - 2010


ABSTRACT:
An efficient method for green synthesis of some 2, 3-dihydro 1H-1, 5-benzodiazepine derivatives has been developed by simple cyclocondensation reaction of o-phenylendiamine with aromatic, cyclic and acyclic ketones as well as 1, 3-ß dicarbonyl compounds in presence of catalytic amount of silica gel under ultrasound irradiation. The title compounds have been characterized by physico-chemical methods and screened for anti-microbial activity in order to evaluate for the effectivity against Crofloxin and Ciclopiroxoamine as standard.


Cite this article:
Chandak BG, Sarpate RV, Chatterjee NR, Baheti KG. Synthesis, Spectral Studies and Biological Activity of Some 1, 5-Benzodiazepine Derivatives. Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 938-941.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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