ABSTRACT:
Since few decades pharmaceutical researchers have introduced different pharmaceutical drug carriers like particulate carriers, polymeric carriers, cellular carriers, etc to meet the different objectives like sustained drug delivery, targeting the different organs like brain, lungs, enhancing the bioavailability, etc. Vesicular carriers are one of the different particulate carriers. Different vesicular carriers include liposomes, niosomes, ethosomes, etc. Researchers substantiated that these vesicular carriers are going to be prominent tools for the administration of the drugs. Among all vesicular carriers Niosomes has wide range of advantages which includes greater chemical stability, ease of manufacturing, handling, less toxic, economical, etc. The major drawback associated with niosomes is its physical stability which can be solved by the new technique i.e. in the form of Proniosomes. The present review article consists of advantages, manufacturing processes, characterizations and applications of proniosomes.