Author(s): D B Doshi, P A Bhatt

Email(s): divyesh_81181@yahoo.com

DOI: Not Available

Address: D. B. Doshi1* and P. A. Bhatt2
1APMC College of Pharmaceutical Education and Research, College Campus, Motipura, Himatnagar-383001, Gujarat 2L.M. College of Pharmacy, Ahmedabad-380009, Gujarat
*Corresponding Author

Published In:   Volume - 3,      Issue - 3,     Year - 2010


ABSTRACT:
Pravastatin sodium (PRS) is a HMG Co A reductase inhibitor, used as a lipid lowering agent. Two simple, sensitive and economical UV spectrophotometric methods have been developed for the estimation of pravastatin sodium in bulk drug and pharmaceutical tablet dosage forms. Methods were based on the first order derivative spectroscopy and area under curve method. Both method obeyed Beer’s law in the concentration range of 10–20 µg/ml. The results obtained with the proposed methods are in good agreement with labeled amounts when tablet dosage forms were analyzed. The proposed methods were validated for analytical method validation parameter as per ICH and US FDA guidance documents. The proposed methods have adequate specificity, sensitivity and reproducibility for quality control assay of pravastatin sodium in bulk and tablet dosage form without any interference from excipients.


Cite this article:
D B Doshi, P A Bhatt. Development and Validation of UV Spectrophotometric Methods for the Estimation of Pravastatin Sodium in Bulk and Tablet Dosage Form. Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 869-871.


Recomonded Articles:

Author(s): Ravindranath S. Misal, Vishawas R. Potphode, Vijay R. Mahajan

DOI: 10.5958/0974-360X.2017.00218.9         Access: Open Access Read More

Author(s): Niharika, Navneet Verma

DOI: 10.5958/0974-360X.2016.00182.7         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): Narendra Chotai, Vishnu Patel, Harsha Patel, Uren Patel, Rajendra Kotadiya

DOI:         Access: Open Access Read More

Author(s): Homendra Kumar Sahu, Kamdev Sen, Raju Patel, Hulash Sahu, Deepika Sahu, Gulshan Sahu, Chandrashekhar Jain, Narayan Prasad Chandra, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00173.1         Access: Open Access Read More

Author(s): Hemlata M. Nimje, Rajesh J. Oswal, Sandip S. Kshirsagar, Manoj Chavan

DOI: Not Available         Access: Open Access Read More

Author(s): Vikram Kumar Sahu, Amit Mishra, Nitin Sharma, Pratap Kumar Sahu, Shubhini A. Saraf

DOI: 10.5958/0974-360X.2017.00048.8         Access: Open Access Read More

Author(s): Rao Rekha, Goswami Anju, Shekhar Shishant, Mahant Sheefali, Nanda Sanju

DOI: Not Available         Access: Open Access Read More

Author(s): H.B. Pagar, U.P. Shinde, Y.S. Agrawal, S.D. Barhate, T.S. Luhade, R.O. Sonawane

DOI: Not Available         Access: Open Access Read More

Author(s): Bahubali N. Patil, Vamshi Krishna Tippavajhala, Girish Pai K

DOI: 10.5958/0974-360X.2019.00140.9         Access: Open Access Read More

Author(s): Pratik N. Shah, Bhavini N. Patel, Chaganbhai N. Patel

DOI: Not Available         Access: Open Access Read More

Author(s): Rajendra Jangde, S. J. Daharwal

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags