Venkatesh P, Hepcy Kalarani D, Dinakar A
Venkatesh P.1*, Hepcy Kalarani D1 and Dinakar A.2
1P. Rami Reddy Memorial College of Pharmacy-Kadapa-516 003, Andhra Pradesh, India.
2Vagdevi College of Pharmacy and Research Centre, Nellore-524 004, Andhra Pradesh, India.
Volume - 3,
Issue - 3,
Year - 2010
An aqueous extract of stem and leaves of Boerhaavia Diffusa (AEBD) was studied for hepatoprotective activity against Swiss albino rats with liver damage induced by Carbon tetrachloride (CCl4) at two dose levels 150 and 300 mg kg-1. AEBD exhibited a significant protective action on the liver evident by a reduction in the elevated levels of serum lyosomal enzymes namely Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Alkaline Phosphatase (ALP) in CCl4 induced hepatotoxicity. Thus AEBD showed a dose dependent hepatoprotective activity.
Cite this article:
Venkatesh P, Hepcy Kalarani D, Dinakar A. Hepatoprotective Activity of an Aqueous Extract of Stem and Leaves of Boerhaavia diffusa Against Carbon Tetra Chloride Induced Hepatotoxicity in Rats. Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 840-842.