Author(s): P Muthumani, R Meera, S Venkataraman, Murugan, N Chidambaranathan, P Devi, B Kameswari, B Eswarapriya

Email(s): meeraharsa@yahoo.com

DOI: Not Available

Address: P. Muthumani1*, R. Meera1, S. Venkataraman1, Murugan1, N. Chidambaranathan2, P. Devi3, B. Kameswari4 and B. Eswarapriya5
1Department of Pharmaceutical Chemistry,
2Department of Pharmacology,
3Department of Pharmacognosy,
4Department of Biochemistry, K. M. College of Pharmacy, Uthangudi, Madurai -625107, Tamilnadu, India , 5Department of Biotechnology,
St. Michael College of Engineering, Sivagangi, Tamilnadu, India
*Corresponding Author

Published In:   Volume - 3,      Issue - 3,     Year - 2010


ABSTRACT:
Para substituted N-aryl anthranilic acid derivatives were synthesized via Ullmann condensation of o-Chlorobenzoic acid with various p-substituted aniline in the presence of cupric oxide (catalyst) and anhydrous potassium carbonate (for removal of hydrogen halide formed during reaction). The synthesized compounds (Ia-Ih) were evaluated the following biological activities Anti-inflammatory, Analgesic activity, Anti-bacterial activity. Organism used: Staphylococcus aureus (MTCC 96) Klebsiella aerogenes (MTCC), E. Coli (MTCC 722) Standard Used: Oflaxacin (10mg/disc)


Cite this article:
P Muthumani, R Meera, S Venkataraman, Murugan, N Chidambaranathan, P Devi, B Kameswari, B Eswarapriya. Anti-inflammatory, Analgesic and Antimicrobial Activity of Some Novel Schiff’s bases of N-aryl anthranilic acid Derivatives. Research J. Pharm. and Tech.3 (3): July-Sept. 2010; Page 740-743.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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