Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Study of Antiulcer Activity of Aerial Parts of Tephrosia spinosa (L.f) Pers

Author(s): K Ilango, R Xavier Arulappa

Email(s): xavilatha@yahoo.co.in

DOI: Not Available

Address: K Ilango1 and R Xavier Arulappa2*
1Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur– 603 203, Kancheepuram District, (T.N)
2*Department of Pharmaceutical Chemistry, K.M .College of Pharmacy, Uthangudi, Madurai – 625 107 (T.N)
*Corresponding Author

Published In:   Volume - 3,      Issue - 2,     Year - 2010

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ABSTRACT:
The effect of methanolic extract of aerial parts of Tephrosia spinosa was investigated in rats to evaluate antiulcer activity by using Indomethacin induced plus pyloric ligation ulcer model. The parameters taken for antiulcer activity were the total gastric volume secretion, ulcer score, total acidity, pH and the ulcer index. The methanolic extract of aerial parts of Tephrosia spinosa showed significantly (P < 0.001) decreased when compared with the control treated group total gastric volume (6.12 ? 0.09) ml, ulcer score (3.17 ? 0.123) total acidity (70.32 ? 2.91) m eq /L/100g.


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Cite this article:
K Ilango, R Xavier Arulappa. Study of Antiulcer Activity of Aerial Parts of Tephrosia spinosa (L.f) Pers. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 631-632.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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