Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Diuretic and Laxative Activities of Methanol Extract of Mimosa pudica Leaves

Author(s): Rekha Rajendran, S Ruby

Email(s): rekhacognosy@rediffmail.com

DOI: Not Available

Address: Rekha Rajendran1* and S Ruby2
Department of Pharmacognosy and Phytochemistry, Mohamed Sathak A. J. College of Pharmacy, Medavakkam, Chennai - 600 119, Tamil Nadu, India
2 Department of Pharmaceutical Chemistry, Nandha college of pharmacy, India.
*Corresponding Author

Published In:   Volume - 3,      Issue - 2,     Year - 2010

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ABSTRACT:
The methanol extract of leaves of Mimosa pudica (Mimosaceae) was screened for diuretic and laxative activities in wistar albino rats. The study suggested that the extract was found to produce significant diuretic as well as laxative activities in dose dependant manner (200 and 400mg/kg p. o.). These activities were comparable with the standard drugs such as Furosemide (10mg/kg p. o.) and Agar-agar (300mg/kg p. o.) respectively. The preliminary phytochemical analysis of methanol extract of leaves of Mimosa pudica revealed the presence of phytoconstituents such as alkaloids, tannins, mucilage and flavonoids. The present study indicates that the observed significant diuretic and laxative activities of Mimosa pudica leaves may be contributed to the phytoconstituents present in it. Further work is in progress to identify the possible mechanisms of action and to identify the lead molecules responsible for diuretic and laxative activities.


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Cite this article:
Rekha Rajendran, S Ruby. Diuretic and Laxative Activities of Methanol Extract of Mimosa pudica Leaves. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 556-558.

Cite(Electronic):
Rekha Rajendran, S Ruby. Diuretic and Laxative Activities of Methanol Extract of Mimosa pudica Leaves. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 556-558.   Available on: https://rjptonline.org/AbstractView.aspx?PID=2010-3-2-44


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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