The present study was designed to investigate the analgesic effects of fruits of Silybum marianum L. Gaertn. The ethylacetate and ethanol extracts of Silybum marianum L. Gaertn fruits showed dose-dependent and significant (P<0.05) increase in pain threshold in tail–immersion test. Moreover, both the extracts (100-200mg/kg) exhibits a dose–dependent inhibition of writhing and also showed a significant (P<0.001) inhibition of both phases of formalin pain test. The phytochemical screening of the extract showed the presence of flavonolignans, flavonoids, fixed oils and proteins.
Cite this article:
Manpreet Kaur, Harinder Kaur. Analgesic Effects of Fruits of Silybum marianum L. Gaertn. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 92-94.