Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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Analgesic Effects of Fruits of Silybum marianum L. Gaertn

Author(s): Manpreet Kaur, Harinder Kaur

Email(s): asrpreet2007@rediffmail.com

DOI: Not Available

Address: Manpreet Kaur1* and Harinder Kaur2
1Department of Pharmaceutical Sciences, Gurusar Sadhar, Ludhiana (Punjab).
2Govt. Institute of Pharmaceutical and Engineering Sciences, Amritsar (Punjab).
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010

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ABSTRACT:
The present study was designed to investigate the analgesic effects of fruits of Silybum marianum L. Gaertn. The ethylacetate and ethanol extracts of Silybum marianum L. Gaertn fruits showed dose-dependent and significant (P<0.05) increase in pain threshold in tail–immersion test. Moreover, both the extracts (100-200mg/kg) exhibits a dose–dependent inhibition of writhing and also showed a significant (P<0.001) inhibition of both phases of formalin pain test. The phytochemical screening of the extract showed the presence of flavonolignans, flavonoids, fixed oils and proteins.


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Cite this article:
Manpreet Kaur, Harinder Kaur. Analgesic Effects of Fruits of Silybum marianum L. Gaertn. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 92-94.


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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