Analgesic Effects of Fruits of Silybum marianum L. Gaertn

Manpreet Kaur; Harinder Kaur

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Analgesic Effects of Fruits of Silybum marianum L. Gaertn

Author(s): Manpreet Kaur, Harinder Kaur

Email(s): asrpreet2007@rediffmail.com

DOI: Not Available

Address: Manpreet Kaur1* and Harinder Kaur2
1Department of Pharmaceutical Sciences, Gurusar Sadhar, Ludhiana (Punjab).
2Govt. Institute of Pharmaceutical and Engineering Sciences, Amritsar (Punjab).
*Corresponding Author

Published In: Volume - 3, Issue - 1, Year - 2010

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ABSTRACT:
The present study was designed to investigate the analgesic effects of fruits of Silybum marianum L. Gaertn. The ethylacetate and ethanol extracts of Silybum marianum L. Gaertn fruits showed dose-dependent and significant (P<0.05) increase in pain threshold in tail–immersion test. Moreover, both the extracts (100-200mg/kg) exhibits a dose–dependent inhibition of writhing and also showed a significant (P<0.001) inhibition of both phases of formalin pain test. The phytochemical screening of the extract showed the presence of flavonolignans, flavonoids, fixed oils and proteins.

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Cite this article:
Manpreet Kaur, Harinder Kaur. Analgesic Effects of Fruits of Silybum marianum L. Gaertn. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 92-94.

Cite(Electronic):
Manpreet Kaur, Harinder Kaur. Analgesic Effects of Fruits of Silybum marianum L. Gaertn. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 92-94. Available on: https://rjptonline.org/AbstractView.aspx?PID=2010-3-1-9