Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)


Submit Article

Analgesic Effects of Fruits of Silybum marianum L. Gaertn

Author(s): Manpreet Kaur, Harinder Kaur

Email(s): asrpreet2007@rediffmail.com

DOI: Not Available

Address: Manpreet Kaur1* and Harinder Kaur2
1Department of Pharmaceutical Sciences, Gurusar Sadhar, Ludhiana (Punjab).
2Govt. Institute of Pharmaceutical and Engineering Sciences, Amritsar (Punjab).
*Corresponding Author

Published In:   Volume - 3,      Issue - 1,     Year - 2010

 View HTML        View PDF

ABSTRACT:
The present study was designed to investigate the analgesic effects of fruits of Silybum marianum L. Gaertn. The ethylacetate and ethanol extracts of Silybum marianum L. Gaertn fruits showed dose-dependent and significant (P<0.05) increase in pain threshold in tail–immersion test. Moreover, both the extracts (100-200mg/kg) exhibits a dose–dependent inhibition of writhing and also showed a significant (P<0.001) inhibition of both phases of formalin pain test. The phytochemical screening of the extract showed the presence of flavonolignans, flavonoids, fixed oils and proteins.


Keywords:

Cite this article:
Manpreet Kaur, Harinder Kaur. Analgesic Effects of Fruits of Silybum marianum L. Gaertn. Research J. Pharm. and Tech. 3(1): Jan. - Mar. 2010; Page 92-94.


Recomonded Articles:

Scrutiny of Antagonistic Microbial and Cytotoxic Promises of Fungal Endophyte Secluded from Pisonia grandis R. Br.

Author(s): Sasikumar C., Mohana S. J., Yasodha S.

DOI: 10.5958/0974-360X.2017.00123.8         Access: Open Access Read More

Antioxidant and Analgesic Activity of Leaf Extracts of Artocarpus heterophyllus

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Formulation Development and Evaluation of Silymarin Gel

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

CNS Depressant and Analgesic Activities of Different Extracts of Tephrosia purpurea Root

Author(s): 1Valli G., Vasanthi A., Vijayalakshmi R., Thanga Thirupathi A

DOI: Not Available         Access: Open Access Read More

Anti-Hyperglycemic activity of the Leaves of Terminalia tomentosa against Normal and Alloxan Induced Diabetic Rats

Author(s): Sravanthi.Alladi, Sarath Prakash D., Ramesh Malothu, Nalini M., Srikanth Rao K.

DOI: Not Available         Access: Open Access Read More

Determination of Antioxidant Capacity, Flavonoids and Total Phenolic Content of Extracts from Atractylis flava Desf

Author(s): Mohamed Akram Melakhessou, Naima Benkiki, Salah Eddine Marref

DOI: 10.5958/0974-360X.2018.00952.6         Access: Open Access Read More

Comparative Study on Anti-inflammatory and Analgesic Activities of Pure Aceclofenac with the Aceclofenac Loaded Mucoadhesive Microparticles in Rats

Author(s): Rajesh. M, Narayanan. N

DOI: 10.5958/0974-360X.2015.00033.5         Access: Open Access Read More

CNS Depressant Effect of Crude Ethanolic Extract of Flowers of Couroupita guianensis Aubl. in Swiss-albino Mice

Author(s): Nowshin Nowaz Rumzhum, Mostafizur Rahman, AFM Rafiu-Ul Islam

DOI: Not Available         Access: Open Access Read More

Synthesis of Some Mannich Bases of 6-Substituted-2-Aminobenzothiazole as Analgesic

Author(s): Bele D.S., Singhvi I.

DOI: Not Available         Access: Open Access Read More

Analgesic Activity of Roots of Aralia racemosa

Author(s): Manpreet Kaur, Harinder Kaur

DOI: Not Available         Access: Open Access Read More

Hepatoprotective and in vivo antioxidant effects of Corchorus depressus (L.) Stocks. (Tiliaceae)

Author(s): Sandeep Kataria1*, Dilsher Kaur2, Shaival Kamalaksha Rao3, Neha Sharma4, Ravi K Khajuria4

DOI: Not Available         Access: Open Access Read More

Screening of Analgesic and Anti-inflammatory Activity of Hydroalcohol Extract of Sida (Indian) Species Root

Author(s): VH Bhaskar, B Sangameswaran, N Balakrishnan, AB Panda, Navin R Raj, A Sathish

DOI:         Access: Open Access Read More

Central Nervous System Depressant and Analgesic Activity of Methanolic Extract of Drypetes roxburghii Wall in Experimental Animal Model

Author(s): Sudharshan SJ, Chinmaya A, Valleesha NC, Prashith Kekuda TR, Rajeshwara AN, Syed Murthuza

DOI:         Access: Open Access Read More

Paracetamol Induced Liver Morphological Changes after Acute Dosing

Author(s): Hudaa Zulfaa Mohd Zainuddin, Laila Ruwaida Mohd Zainuddin

DOI: 10.5958/0974-360X.2015.00064.5         Access: Open Access Read More

Synthesis, Analgesic and Anti-inflammatory Activity of Some Novel Derivatives of Naproxen

Author(s): Jennifer Fernandes, Satyajeet Singh, Abhishek Kumar, Pankaj Kumar

DOI: Not Available         Access: Open Access Read More

In vivo Antioxidant and Modulating Enzymes of Wattakaka Volubilis and Kaempferol against Aluminium Sulphate Induced in Liver Toxicity

Author(s): Usharani S , R. Anuradha

DOI: 10.5958/0974-360X.2018.00512.7         Access: Open Access Read More

Antioxidant and Hepatoprotective Activity of Root extract of Baliospermum montanum (Willd) Muell Arg

Author(s): Ahirwar B, Ahirwar D

DOI: 10.5958/0974-360X.2019.00452.9         Access: Open Access Read More

In silico prediction of Anti-apoptotic BCL-2 proteins Modulation by Afzelin in MDA-MB-231 Breast cancer cell

Author(s): Eva Rachmi, Basuki Bambang Purnomo, Agustina Tri Endharti, Loeki Enggar Fitri

DOI: 10.5958/0974-360X.2020.00171.7         Access: Closed Access Read More

Holarrhena antidysenterica Linn. – A Review

Author(s): Gopinath G, Thirumal M, P. R. Kumar

DOI: 10.5958/0974-360X.2020.00362.5         Access: Closed Access Read More

Analgesic and Anti-Inflammatory Activities of Anthocephalus Cadamba Roxb. Leaves in Wistar Rats

Author(s): RS Bachhav, VV Buchake, RB Saudagar

DOI:         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Quick Links

Latest Issues

Popular Articles


Recent Articles



Effect of Emblica officinalis (Amla) on Monosodium Glutamate (MSG) Induced Uterine Fibroids in Wistar Rats
Regulatory requirements for Post approval changes in Japan, Canada and Malaysia
Curcumin Potentiates Therapeutic Efficacy of Metformin: A Preclinical Study in STZ-NA Induced Hyperglycemia in Wistar Rats
Synthesis and Antibacterial activity of some newer Benzimidazole derivatives
The Correction Methods of the Intestinal Microflora in Chronic Colonic Stasis by Siphon Enema and Probiotics as a Means of the Hirschsprung-associated Enterocolitis Prevention
Stability Indicating HPTLC Determination of Tadalafil Hydrochloride in Bulk Drug and Pharmaceutical Formulations
Biochemical Evaluation of Antidiabetic properties of Strychnos potatorum Seeds extract studied in High Fat Diet Fed- Low dose Streptozotocin induced experimental type 2 diabetes in Rats
In Vitro Antioxidant and Antibacterial Screening of flowers Extract from Cassia auriculata Linn.
Preparation and Evaluation of Mouth Dissolving Tablets of Loratadine by Direct Compression Method
Phytochemical assessment and Bioactivity of alcoholic extract seed of Louranthus europpaeus
Design, Development and Evaluation of Solid Form of Liquid Self-Nanoemulsifying Formulation for improving the Oral Bioavailability of Itraconazole
Optimization and Characterization of Exopolysaccharide from Marine Soil Bacteria
Development and Validation of an RP-HPLC Analytical Method for Determination of Lisinopril in Full and Split Tablets
Preparation of Silver Nanoparticles from Bael (Aegle marmelos) Leaves Extract and their Doping with Multiwalled Carbon Nanotubes for Antibacterial Utility
An effective multicomponent synthesis of 2,6-dihydro-2,6-diimino-4,8-bis (phenylamino) pyrimido [2,1-b] [1,3] thiazine-3,7-dicarbonitrile
Synthesis, Characterization and Anti-oxidant Activity of Novel Phenylhydrazine derivatives containing carbonyl group on β- carbon
Pharmacognostical Evaluation and HPTLC Analysis of Two Medicinally important Secondary Metabolites in Bauhinia variegata Leaves from Gorakhpur District in Summer Season
Formulation, Characterization of Anticancer Nanoemulsion containing Trigonella foenum-graecum L. Seed oil
Endoscopic Retrograde Cholangiopancreatography in Central Iraq: A Retrospective Single- Center Study
Biosynthesis of Gold Nanoparticles using Leaf Extract of Desmodium gangeticum and their Antioxidant Activity

Tags


About Journal

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
Read More  

Visitors

Today: 1674
Yesterday: 10681
Total: 1655004