Aceclofenac is a non steroidal anti-inflammatory drug and paracetamol is an analgesic and antipyretic drug. Simple, precise, rapid and selective simultaneous equation and Q- analysis UV spectrophotometric methods have been developed for the simultaneous determination of aceclofenac and paracetamol from combined tablet dosage forms. The methods involve solving of simultaneous equations and Q-value analysis based on measurement absorptivity at 274nm, 267.5nm and 245 nm respectively. The method shows good linearity, accuracy and reproducibility. Results of analysis validated statistically and by recovery studies.
Cite this article:
Deepali Gharge, Chandrakant Raut, Pandurang Dhabale. Simultaneous Estimation of Aceclofenac and Paracetamol in Solid Dosage Form by UV Spectrophotometry. Research J. Pharm. and Tech. 3(1): Jan.-Mar. 2010; Page 247-250.