Topical gels are semisolid systems in which a liquid phase is constrained within a three dimensional polymeric matrix of natural or synthetic gum in which high degree of physical or chemical cross linking has been established. Topical gels present ideal candidate for variety of application due to its intermediate behavior between solid and liquid materials. Topical gels have received significant attention over the past few decades because it is a topic of interest to the scientists working in industry, research and development, education, drug control administration and professional. The objective of this article is to review the fundamental and present advances in topical gels including classification and method of preparation. The application of hydrogel on drug delivery system is separately discussed. Special emphasis is given on its classification, method of preparation and evaluation parameters.
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